Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14469459 | 0.88 | KDM4E (0.56) | KDM4EPOLBFAAHALDH1A1MAPK1 | |
| SCHEMBL14469468 | 0.86 | KDM4E (0.48) | KDM4EPOLBALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL14469449 | 0.85 | KMT2A (0.53) | KDM4EPOLBFAAHALDH1A1MAPK1 | |
| SCHEMBL14469568 | 0.84 | S1PR5 (0.52) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP2D6 | |
| SCHEMBL14469549 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1KMT2AMEN1GAA | |
| SCHEMBL14469456 | 0.83 | SMN1; SMN2 (0.50) | KDM4EPOLBFAAHALDH1A1KMT2A | |
| SCHEMBL14469475 | 0.83 | ALDH1A1 (0.47) | KDM4EPOLBMTNR1BALDH1A1MAPK1 | |
| SCHEMBL14469562 | 0.83 | L3MBTL1 (0.47) | KDM4EPOLBALDH1A1MAPK1KMT2A | |
| SCHEMBL14469452 | 0.83 | SMN1; SMN2 (0.47) | KDM4EKMT2AMEN1SMN1; SMN2CYP3A4 | |
| SCHEMBL14469476 | 0.82 | FAAH (0.50) | KDM4EPOLBFAAHALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075555-A2 | COMBINATION OF AN H3 ANTAGONIST/INVERSE AGONIST AND AN APPETITE SUPPRESSANT | SCHERING CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |