Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 4/20 | 0.57 |
| ▸ | CTSD | P07339 | 3/20 | 0.56 |
| ▸ | GUSB | P08236 | 2/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1801571 | 0.88 | CTSD (0.45) | CXCR3CTSDGUSBNOD1NPSR1 | |
| SCHEMBL1803118 | 0.86 | MAPT (0.59) | CTSDNPSR1TSHRALDH1A1LMNA | |
| SCHEMBL1802569 | 0.84 | SMN1; SMN2 (0.50) | CXCR3CTSDGUSBNPSR1ALDH1A1 | |
| SCHEMBL1802357 | 0.81 | F2R (0.41) | CXCR3CTSDGUSBNPSR1TSHR | |
| SCHEMBL1800064 | 0.81 | CTSD (0.46) | CXCR3CTSDNPSR1TSHRALDH1A1 | |
| SCHEMBL4996791 | 0.78 | CXCR3 (0.57) | CXCR3CTSDGUSBNOD1NPSR1 | |
| SCHEMBL1385523 | 0.73 | KDM4E (0.71) | CTSDGUSBTSHRALDH1A1LMNA | |
| SCHEMBL1801438 | 0.69 | SMN1; SMN2 (0.49) | CXCR3CTSDNPSR1ALDH1A1LMNA | |
| SCHEMBL14470429 | 0.69 | F2R (0.61) | CXCR3CTSDGUSBNOD1NPSR1 | |
| SCHEMBL5037413 | 0.68 | KDM4E (0.62) | TSHRALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7951957-B2 | Substituted benzimidazoles and their use for inducing apoptosis | BASILEA PHARMACEUTICA AG (CH) | 2011-05-31 | — | — | US | claimed |