SCHEMBL1448599

SCHEMBL1448599

CCCCC(O)(O)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HTR7 P34969 1/20 0.35
HTR2B P41595 1/20 0.35
SIGMAR1 Q99720 2/20 0.34
HSP90AA1 P07900 2/20 0.34
HSP90AB1 P08238 2/20 0.34
DRD2 P14416 2/20 0.32
DRD4 P21917 2/20 0.32
DRD3 P35462 2/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
PGR P06401 1/20 0.32
TRPA1 O75762 2/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GABRP O00591 1/20 0.30
GABRD O14764 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29111158 0.86 PNMT (0.40) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29111154 0.81 PNMT (0.36) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8060281 0.79 PNMT (0.41) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL3786405 0.76 PNMT (0.38) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6350486 0.75 PNMT (0.35) PNMTNPC1RAB9ADRD2DRD4
Hydrochloric Acid SCHEMBL6557752 0.73 PNMT (0.34) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL704466 0.73 PNMT (0.36) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL2043313 0.73 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5837265 0.73 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL7111117 0.73 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3336145-B1 POLYCARBONATE RESIN COMPOSITION AND MOLDED POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2023-11-01 EP disclosed
CN-112714783-B Thermoplastic resin composition 日本A&L株式会社 2022-11-11 CN disclosed
US-20220289933-A1 Compositions With Improved Dielectric Strength SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-09-15 US disclosed
EP-4017911-A1 COMPOSITIONS WITH IMPROVED DIELECTRIC STRENGTH SHPP Global Technologies B.V. (NL) 2022-06-29 EP disclosed
EP-2578636-B2 POLYCARBONATE RESIN COMPOSITION AND MOLDED POLYCARBONATE RESIN IDEMITSU KOSAN CO (JP) 2022-06-22 EP disclosed
CN-114634695-A Resin composition and method for producing resin composition 索尼公司 2022-06-17 CN disclosed
CN-114466898-A Composition with improved dielectric strength 高新特殊工程塑料全球技术有限公司 2022-05-10 CN disclosed
CN-110506078-B Resin composition and method for producing resin composition 索尼公司 2022-03-29 CN disclosed
US-10995213-B2 Polycarbonate resin composition and molded polycarbonate resin IDEMITSU KOSAN CO., LTD. (JP) 2021-05-04 US disclosed
CN-112714783-A Thermoplastic resin composition 日本A&L株式会社 2021-04-27 CN disclosed
US-6048931-A Polycarbonate resin composition KANEKA CORPORATION (JP) 2000-04-11 US disclosed
EP-0709432-B1 Polycarbonate resin composition and exterior automotive trim using same IDEMITSU PETROCHEMICAL CO (JP) 2000-01-12 EP disclosed
EP-0893475-A1 FLAME RETARDANT PLASTIC RESIN COMPOSITION KANEKA CORPORATION (JP) 1999-01-27 EP disclosed
EP-0884366-A1 FLAME-RETARDANT THERMOPLASTIC RESIN COMPOSITION KANEKA CORPORATION (JP) 1998-12-16 EP disclosed
EP-0625547-B1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO (JP) 1998-10-14 EP disclosed
EP-0861873-A1 POLYCARBONATE RESIN COMPOSITION KANEKA CORPORATION (JP) 1998-09-02 EP disclosed
US-5637643-A POLYESTER, RUBBER ELASTOMER, AND SURFACE TREATED TALC PARTICLES IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1997-06-10 US disclosed
EP-0709432-A2 Polycarbonate resin composition and exterior automotive trim using same IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-05-01 EP disclosed
US-5449710-A Blends with metal salts of perfluoroalkanesulfonic acid and organopolysiloxane with optional fillers to prevent dripping IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-09-12 US disclosed
EP-0625547-A1 Flame retardative polycarbonate resin composition IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1994-11-23 EP disclosed