Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060281 | 0.80 | PNMT (0.41) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL29111158 | 0.79 | PNMT (0.40) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL29111154 | 0.77 | PNMT (0.36) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL1448599 | 0.76 | PNMT (0.42) | PNMTNPC1RAB9AHTR7HTR2B | |
| SCHEMBL704466 | 0.74 | PNMT (0.36) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hexane SCHEMBL8201767 | 0.73 | PNMT (0.47) | PNMTNPC1RAB9AHTR7HTR2B | |
| Hexane SCHEMBL8572947 | 0.70 | PNMT (0.47) | PNMTNPC1RAB9AHTR7HTR2B | |
| Fluorene SCHEMBL28315043 | 0.70 | TSHR (0.53) | NPC1RAB9ADRD2SIGMAR1ADRA1D | |
| Fluorene SCHEMBL25291666 | 0.70 | MAOA (0.50) | PNMTNPC1RAB9AHTR2BDRD2 | |
| SCHEMBL5837265 | 0.69 | PNMT (0.49) | PNMTNPC1RAB9AHTR7HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198985-B2 | Bimodal star polymer architectures as fluorescent and MRI imaging reagents | VANDERBUILT UNIVERSITY (US) | 2015-12-01 | — | — | US | disclosed |
| US-20130029369-A1 | BIMODAL STAR POLYMER ARCHITECTURES AS FLUORESCENT AND MRI IMAGING REAGENTS | NATIONAL SCIENCE FOUNDATION | 2013-01-31 | — | — | US | disclosed |
| WO-2010135666-A1 | BIMODAL STAR POLYMER ARCHITECTURES AS FLUORESCENT AND MRI IMAGING REAGENTS | VANDERBILT UNIVERSITY (US) | 2010-11-25 | — | — | WO | disclosed |