Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.43 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223715 | 0.81 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL14486908 | 0.76 | TAS1R3 (0.54) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL20397416 | 0.73 | KCNQ3 (0.37) | MEN1KMT2ARAB9AKDM4EKCNQ3 | |
| SCHEMBL21672318 | 0.72 | PGK1 (0.45) | MEN1KMT2ARAB9AHPGDALDH1A1 | |
| SCHEMBL31136727 | 0.70 | ROCK1 (0.40) | MEN1KMT2ARAB9AHPGDLMNA | |
| SCHEMBL17801307 | 0.70 | KCNMA1 (0.64) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL4735459 | 0.70 | TUBB4A (0.49) | MEN1KMT2ARAB9AL3MBTL1KCNQ3 | |
| SCHEMBL9944145 | 0.69 | MEN1 (0.67) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL16879643 | 0.69 | ATR (0.44) | — | |
| SCHEMBL703300 | 0.69 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729472-B1 | CARBOXYLIC ACID DERIVATIVES WITH AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |
| EP-2729472-B1 | CARBOXYLIC ACID DERIVATIVES WITH AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI SA (FR) | 2016-08-24 | — | — | EP | disclosed |
| US-8907093-B2 | Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring | SANOFI (FR) | 2014-12-09 | — | — | US | disclosed |
| US-8907093-B2 | Carboxylic acid derivatives having an oxazolo[4,5-c]pyridine ring | SANOFI (FR) | 2014-12-09 | — | — | US | disclosed |
| EP-2729472-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2014-05-14 | — | — | EP | disclosed |
| US-20130023558-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-c]PYRIDINE RING | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| US-20130023558-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-c]PYRIDINE RING | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| WO-2013004824-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013004824-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2013-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023558-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-c]PYRIDINE RING | OXGR1, CXCR5, CXCR1 | TAS1R3 2180/4885TAS1R1 2127/4885TAS1R2 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.