Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.48 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14486908 | 0.81 | TAS1R3 (0.54) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL14486152 | 0.81 | TAS1R3 (0.52) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL23330537 | 0.79 | F10 (0.56) | MEN1KMT2ARAB9AALDH1A1LMNA | |
| SCHEMBL23330872 | 0.77 | MEN1 (0.48) | MEN1KMT2ARAB9APOLBHPGD | |
| SCHEMBL23331032 | 0.74 | KCNQ3 (0.51) | MEN1KMT2ARAB9APOLBHPGD | |
| SCHEMBL23330837 | 0.72 | KCNMA1 (0.51) | KMT2ARAB9APOLBALDH1A1LMNA | |
| SCHEMBL17111799 | 0.72 | NFKB1 (0.40) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL23331258 | 0.71 | PTK2 (0.43) | MEN1KMT2APOLBHPGDALDH1A1 | |
| SCHEMBL23330833 | 0.70 | GLS (0.38) | MEN1KMT2ARAB9APOLBHPGD | |
| SCHEMBL23330676 | 0.70 | ADORA3 (0.49) | MEN1KMT2ARAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729475-B1 | Carboxylic acid derivatives with an oxazolo[4,5-d]pyrimidine ring | SANOFI SA (FR) | 2015-06-10 | — | — | EP | disclosed |
| EP-2729475-B1 | Carboxylic acid derivatives with an oxazolo[4,5-d]pyrimidine ring | SANOFI SA (FR) | 2015-06-10 | — | — | EP | disclosed |
| US-9040544-B2 | 2,5-substituted oxazolopyrimidine derivatives | SANOFI (FR) | 2015-05-26 | — | — | US | disclosed |
| US-8846690-B2 | Heterocyclic carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| US-8846692-B2 | Carboxylic acid derivatives having a 2,5-substituted oxazolopyrimidine ring | SANOFI (FR) | 2014-09-30 | — | — | US | disclosed |
| EP-2523963-B1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES AS EDG-1 AGONISTS | SANOFI SA (FR) | 2014-08-27 | — | — | EP | disclosed |
| US-8735402-B2 | Cycloalkyloxycarboxylic acid derivatives | SANOFI (FR) | 2014-05-27 | — | — | US | disclosed |
| US-8735402-B2 | Cycloalkyloxycarboxylic acid derivatives | SANOFI (FR) | 2014-05-27 | — | — | US | disclosed |
| EP-2729475-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2014-05-14 | — | — | EP | disclosed |
| EP-2523962-B1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI SA (FR) | 2013-11-27 | — | — | EP | disclosed |
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | SANOFI (FR) | 2013-01-24 | — | — | US | disclosed |
| WO-2013004828-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2013-01-10 | — | — | WO | disclosed |
| WO-2013004828-A1 | CARBOXYLIC ACID DERIVATIVES HAVING AN OXAZOLO[4,5-C]PYRIDINE RING | SANOFI (FR) | 2013-01-10 | — | — | WO | disclosed |
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| EP-2523963-A1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| EP-2523960-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011086081-A1 | 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE DERIVATIVES | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011086080-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023545-A1 | CYCLOALKYLOXYCARBOXYLIC ACID DERIVATIVES | C3AR1, CCR2, C5 | TAS1R3 2808/4885TAS1R1 2491/4885TAS1R2 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.