Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14495658 | 0.80 | PLAU (0.47) | POLBMEN1KMT2AEGLN1ALDH1A1 | |
| SCHEMBL15119425 | 0.77 | EGLN2 (0.44) | EGLN2FTOHTTMEN1KMT2A | |
| SCHEMBL2179962 | 0.77 | DHODH (0.58) | HTTMEN1KMT2ADHODHKDM4E | |
| SCHEMBL1669341 | 0.77 | SHMT2 (0.45) | EGLN2FTOSHMT2EGLN1DHODH | |
| SCHEMBL4712895 | 0.74 | ALDH1A1 (0.66) | EGLN2FTOHTTMEN1KMT2A | |
| SCHEMBL5512445 | 0.74 | L3MBTL1 (0.47) | EGLN2FTOPOLBHTTMEN1 | |
| SCHEMBL13978034 | 0.73 | KDM4E (0.53) | EGLN2FTOSHMT2POLBKMT2A | |
| SCHEMBL4543587 | 0.73 | RAB9A (0.54) | EGLN2FTOPOLBHTTMEN1 | |
| SCHEMBL31300330 | 0.73 | NAPRT (0.49) | EGLN2FTOSHMT2POLBHTT | |
| SCHEMBL4200887 | 0.73 | P2RX7 (0.47) | EGLN2FTOSHMT2POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064553-A2 | THIAZOLE DERIVATIVES AS CXCR3 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2007-06-07 | — | — | WO | disclosed |