SCHEMBL1450108

SCHEMBL1450108

c1coc(OP(Oc2ccco2)Oc2ccco2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.36
MMP1 P03956 1/20 0.35
MMP9 P14780 1/20 0.35
MMP12 P39900 1/20 0.35
ALDH1A1 P00352 3/20 0.32
POLB P06746 3/20 0.32
MEN1 O00255 2/20 0.32
THRB P10828 2/20 0.32
RECQL P46063 2/20 0.32
KMT2A Q03164 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
APEX1 P27695 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22097305 0.78
SCHEMBL6847362 0.76
SCHEMBL3890503 0.75 TP53 (0.34) TP53MMP1MMP9MMP12
SCHEMBL1326408 0.75 TP53 (0.41) TP53MMP1MMP9MMP12ALDH1A1
Water SCHEMBL29272691 0.72 TP53 (0.39) TP53MMP1MMP9MMP12ALDH1A1
Water SCHEMBL29272692 0.72 TP53 (0.39) TP53MMP1MMP9MMP12ALDH1A1
SCHEMBL826030 0.70
SCHEMBL10791737 0.70
SCHEMBL29033107 0.70 ALDH1A1 (0.39) TP53MMP1MMP9MMP12ALDH1A1
SCHEMBL3128596 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11411251-B2 Electrolyte, lithium secondary battery including the electrolyte, and method of manufacturing the electrolyte SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-08-09 US claimed
EP-3667773-A1 ELECTROLYTE, LITHIUM SECONDARY BATTERY INCLUDING THE ELECTROLYTE, AND METHOD OF MANUFACTURING THE ELECTROLYTE Samsung SDI Co., Ltd. (KR) 2020-06-17 EP claimed
CN-111293360-A Electrolyte and lithium secondary battery comprising the same 三星电子株式会社 2020-06-16 CN claimed
US-20200185775-A1 ELECTROLYTE, LITHIUM SECONDARY BATTERY INCLUDING THE ELECTROLYTE, AND METHOD OF MANUFACTURING THE ELECTROLYTE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-06-11 US claimed
US-11411251-B2 Electrolyte, lithium secondary battery including the electrolyte, and method of manufacturing the electrolyte SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-08-09 US disclosed
EP-3667773-A1 ELECTROLYTE, LITHIUM SECONDARY BATTERY INCLUDING THE ELECTROLYTE, AND METHOD OF MANUFACTURING THE ELECTROLYTE Samsung SDI Co., Ltd. (KR) 2020-06-17 EP disclosed
CN-111293360-A Electrolyte and lithium secondary battery comprising the same 三星电子株式会社 2020-06-16 CN disclosed
US-20200185775-A1 ELECTROLYTE, LITHIUM SECONDARY BATTERY INCLUDING THE ELECTROLYTE, AND METHOD OF MANUFACTURING THE ELECTROLYTE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-06-11 US disclosed
US-20200185775-A1 ELECTROLYTE, LITHIUM SECONDARY BATTERY INCLUDING THE ELECTROLYTE, AND METHOD OF MANUFACTURING THE ELECTROLYTE SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-06-11 US disclosed
US-9242974-B2 Processes for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives ENANTA PHARMACEUTICALS, INC. (US) 2016-01-26 US disclosed
US-20140073797-A1 PROCESSES FOR THE PREPARATION OF 2-FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES ENANTA PHARMACEUTICALS, INC. (US) 2014-03-13 US disclosed
US-8552162-B2 Processes for the preparation of 2 fluoro 6-11 bicyclic erythromycin derivatives ENANTA PHARMACEUTICALS, INC. (US) 2013-10-08 US disclosed
US-20040171818-A1 Processes for the preparation of 6-11 bicyclic erythromycin derivatives ENANTA PHARMACEUTICALS, INC. 2004-09-02 US disclosed
EP-1265909-A2 PROCESS FOR THE PREPARATION OF 6-O-PROPARGYL ERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 2002-12-18 EP disclosed
EP-1257531-A2 METHOD FOR THE PREPARATION OF CARBOTHIOIC ACIDS Abbott Laboratories (US) 2002-11-20 EP disclosed
US-20020133032-A1 Method for the preparation of fluticasone and related 17beta-carbothioic esters using a novel carbothioic acid synthesis and novel purification methods ABBOTT LABORATORIES 2002-09-19 US disclosed
US-20020091107-A1 Oxazolidinone antibacterial agents ABBOTT LABORATORIES 2002-07-11 US disclosed
WO-2002020515-A1 OXAZOLIDINONE ANTIBACTERIAL AGENTS ABBOTT LABORATORIES (US) 2002-03-14 WO disclosed
WO-2001077134-A2 PROCESS FOR THE PREPARATION OF 6-O-PROPARGYL ERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 2001-10-18 WO disclosed
WO-2001062722-A2 METHOD FOR THE PREPARATION OF FLUTICASONE AND RELATED 17BETA-CARBOTHIOIC ESTERS USING A NOVEL CARBOTHIOIC ACID SYNTHESIS AND NOVEL PURIFICATION METHODS ABBOTT LABORATORIES (US) 2001-08-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200185775-A1 ELECTROLYTE, LITHIUM SECONDARY BATTERY INCLUDING THE ELECTROLYTE, AND METHOD OF MANUFACTURING THE ELECTROLYTE RER1, CLCN2, NHERF1 TP53 1827/4885MMP1 2208/4885MMP9 700/4885
US-20020133032-A1 Method for the preparation of fluticasone and related 17beta-carbothioic esters using a novel carbothioic acid synthesis and novel purification methods HSD17B7, CYP17A1, NR5A1 TP53 3419/4885MMP1 1346/4885MMP9 2896/4885
US-11411251-B2 Electrolyte, lithium secondary battery including the electrolyte, and method of manufacturing the electrolyte RER1, CLCN2, NHERF1 TP53 1827/4885MMP1 2208/4885MMP9 700/4885
US-20040171818-A1 Processes for the preparation of 6-11 bicyclic erythromycin derivatives CYP2B6, CYP7A1, CYP2D6 TP53 4882/4885MMP1 3029/4885MMP9 2168/4885
US-20140073797-A1 PROCESSES FOR THE PREPARATION OF 2-FLUORO 6-11 BICYCLIC ERYTHROMYCIN DERIVATIVES CYP2F1, CYP2B6, CYP4F11 TP53 4872/4885MMP1 2908/4885MMP9 3735/4885
US-20020091107-A1 Oxazolidinone antibacterial agents OXA1L, TOP1, MT-ND1 TP53 3958/4885MMP1 1191/4885MMP9 2470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.