Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14517789 | 0.94 | RAB9A (0.33) | RAB9ASMN1; SMN2ELANENPY5RNPC1 | |
| SCHEMBL14517826 | 0.91 | ELANE (0.31) | ELANE | |
| SCHEMBL14543063 | 0.90 | NPY5R (0.33) | RAB9ASMN1; SMN2ELANENPY5RNPC1 | |
| SCHEMBL5428667 | 0.90 | ALDH1A1 (0.35) | RAB9ASMN1; SMN2NPY5RNPC1KDM4E | |
| SCHEMBL5427057 | 0.90 | ELANE (0.33) | ELANE | |
| SCHEMBL14517827 | 0.88 | ELANE (0.32) | ELANE | |
| SCHEMBL13946832 | 0.88 | ELANE (0.34) | ELANE | |
| SCHEMBL14517839 | 0.87 | IDO1 (0.38) | ELANE | |
| SCHEMBL14517849 | 0.86 | ELANE (0.32) | ELANE | |
| SCHEMBL4510767 | 0.86 | FAAH (0.33) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205291-B2 | High mouth absorption; antibiotics against gramnegative, grampositive bacteria espscially Staphlococcus pneumonia, Hemophilus influenza | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-17 | — | — | US | disclosed |