Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Thiosulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.38 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiosulfuric Acid SCHEMBL230065 | 0.90 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Thiosulfuric Acid SCHEMBL28268652 | 0.89 | TSHR (0.47) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Thiosulfuric Acid SCHEMBL4209172 | 0.86 | MEN1 (0.44) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Thiosulfuric Acid SCHEMBL230064 | 0.86 | MEN1 (0.44) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Sulfuric Acid SCHEMBL8074036 | 0.85 | TSHR (0.50) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Sulfuric Acid SCHEMBL28097811 | 0.85 | TSHR (0.50) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Thiosulfuric Acid SCHEMBL28143283 | 0.83 | MEN1 (0.41) | MEN1KMT2AALDH1A1TSHRCA5A | |
| Sulfuric Acid SCHEMBL600964 | 0.81 | TSHR (0.69) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Sulfuric Acid SCHEMBL29229401 | 0.81 | TSHR (0.47) | MEN1KMT2AALDH1A1TSHRCA4 | |
| Sulfuric Acid SCHEMBL28110198 | 0.81 | TSHR (0.47) | MEN1KMT2AALDH1A1TSHRCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4411737-A | POST-TREATMENT WITH SODIUM SULFITE, SODIUM SULFIDE AND SODIUM CARBONATE | OWENS-ILLINOIS, INC. (US) | 1983-10-25 | — | — | US | claimed |
| US-20240150367-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2024-05-09 | — | — | US | disclosed |
| US-11945824-B2 | Heterocyclic compounds as anti-viral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| WO-2023180189-A1 | MPRO TARGETING ANTIVIRAL COMPOUNDS | EXSCIENTIA AI LIMITED (GB) | 2023-09-28 | — | — | WO | disclosed |
| CN-114026105-B | Antibacterial aminoglycoside derivative | 卓和药业集团股份有限公司 | 2023-09-26 | — | — | CN | disclosed |
| US-20230029252-A1 | FUCOSYLATED CHONDROITIN SULFATE OLIGOSACCHARIDE, PREPARATION METHOD THEREFOR, COMPOSITION THEREOF AND USE THEREOF | Yantai Dongcheng Biochemicals Co., Ltd (CN) | 2023-01-26 | — | — | US | disclosed |
| US-20230023377-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | JAPAN TOBACCO INC. (JP) | 2023-01-26 | — | — | US | disclosed |
| US-20220227802-A1 | ANTIBACTERIAL AMINOGLYCOSIDE DERIVATIVES | Zhuohe Pharmaceutical Group Co., Ltd (CN) | 2022-07-21 | — | — | US | disclosed |
| CN-110256469-B | Pyrrolobenzodiazepines and conjugates thereof | 麦迪穆有限责任公司 | 2022-05-17 | — | — | CN | disclosed |
| WO-2022086840-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20050267134-A1 | Non-nucleotide composition and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2005-12-01 | — | — | US | disclosed |
| US-20050159388-A1 | Non-nucleotide compositions and method for inhibiting platelet aggregation | INSPIRE PHARMACEUTICALS, INC. | 2005-07-21 | — | — | US | disclosed |
| US-20050148623-A1 | Prevent reproduct of aids virus | ABBVIE INC. | 2005-07-07 | — | — | US | disclosed |
| WO-2005058841-A2 | HIV PROTEASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 2005-06-30 | — | — | WO | disclosed |
| WO-2005040174-A1 | TETRAHYDRO-FURO`3,4-D!DIOXOLE COMPOUNDS AND COMPOSITIONS AND METHOD FOR INHIBITING PLATELET AGGREGATION | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
| WO-2005039590-A1 | NON-NUCLEOTIDE COMPOSITIONS AND METHOD FOR TREATING PAIN | INSPIRE PHARMACEUTICALS, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
| US-5700365-A | Crosslinked polyacrylamide gels with high monomer: crosslinker ratios | AMRESCO INC. (US) | 1997-12-23 | — | — | US | disclosed |
| EP-0764269-A2 | CROSSLINKED POLYACRYLAMIDE GELS WITH HIGH MONOMER: CROSSLINKER RATIOS | Amresco, Inc. (US) | 1997-03-26 | — | — | EP | disclosed |
| WO-1996032628-A9 | CROSSLINKED POLYACRYLAMIDE GELS WITH HIGH MONOMER: CROSSLINKER RATIOS | — | 1997-01-30 | — | — | WO | disclosed |
| WO-1996032628-A2 | CROSSLINKED POLYACRYLAMIDE GELS WITH HIGH MONOMER: CROSSLINKER RATIOS | AMRESCO, INC. (US) | 1996-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227802-A1 | ANTIBACTERIAL AMINOGLYCOSIDE DERIVATIVES | ATP6V1B1, ABCB11, RPN2 | MEN1 4260/4885KMT2A 4247/4885ALDH1A1 1148/4885 |
| US-20050148623-A1 | Prevent reproduct of aids virus | SERPINB1, PRSS1, SERPINA3 | MEN1 2754/4885KMT2A 2273/4885ALDH1A1 1209/4885 |
| US-20230023377-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USES THEREOF | REN, PKD1, NPR1 | MEN1 218/4885KMT2A 3608/4885ALDH1A1 985/4885 |
| US-20050267134-A1 | Non-nucleotide composition and method for inhibiting platelet aggregation | P2RY12, P2RY11, P2RY13 | MEN1 3549/4885KMT2A 4586/4885ALDH1A1 3381/4885 |
| US-20230029252-A1 | FUCOSYLATED CHONDROITIN SULFATE OLIGOSACCHARIDE, PREPARATION METHOD THEREFOR, COMPOSITION THEREOF AND USE THEREOF | FUCA1, FUCA2, CSGALNACT1 | MEN1 2364/4885KMT2A 3729/4885ALDH1A1 1203/4885 |
| US-20240150367-A1 | NITROGEN-CONTAINING SPIRO CYCLIC COMPOUNDS AND PHARMACEUTICAL USE THEREOF | REN, PKD1, NPR1 | MEN1 204/4885KMT2A 3544/4885ALDH1A1 936/4885 |
| US-20050159388-A1 | Non-nucleotide compositions and method for inhibiting platelet aggregation | P2RY12, P2RY11, P2RY13 | MEN1 3712/4885KMT2A 4496/4885ALDH1A1 3046/4885 |
| US-11945824-B2 | Heterocyclic compounds as anti-viral agents | VIP, ACE, FURIN | MEN1 1492/4885KMT2A 2438/4885ALDH1A1 1686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.