Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599665 | 0.88 | TAAR1 (0.57) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL4208734 | 0.82 | ALDH1A1 (0.62) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL17205705 | 0.81 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL8168115 | 0.81 | ALDH1A1 (0.67) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL24092698 | 0.80 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL7932225 | 0.80 | CYP1A2 (0.66) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL28464370 | 0.80 | ALDH1A1 (0.59) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL6409250 | 0.80 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL906527 | 0.79 | CYP1A2 (0.81) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 | |
| SCHEMBL5348698 | 0.79 | CYP1A2 (0.90) | CYP1A2CYP3A4CYP2D6ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | NAFTCHI N E | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082918-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS AND COMPOUNDS WITH MULTIPLE ACTIVITIES | ADRB2, ADRB1, CHRNA7 | CYP1A2 552/4885CYP3A4 658/4885CYP2D6 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.