Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 1.00 |
| ▸ | RAB9A | P51151 | 13/20 | 1.00 |
| ▸ | NPC1 | O15118 | 11/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 2/20 | 1.00 |
| ▸ | RELA | Q04206 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | HCRTR1 | O43613 | 1/20 | 1.00 |
| ▸ | CASP3 | P42574 | 1/20 | 1.00 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 9/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930785 | 0.83 | ALDH1A1 (1.00) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL122784 | 0.82 | APP (0.81) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7059841 | 0.80 | ALDH1A1 (0.73) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8889974 | 0.80 | APP (0.79) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13762461 | 0.80 | KDM4E (0.70) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13930781 | 0.80 | ALDH1A1 (0.71) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL720619 | 0.80 | RAB9A (0.71) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3263307 | 0.80 | KDM4E (0.71) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6689179 | 0.79 | APP (0.71) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2368770 | 0.78 | MAPT (0.63) | KDM4EALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | EDIGENE BIOTECHNOLOGY, INC. (CN) | 2021-07-22 | — | — | US | disclosed |
| US-20110190492-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190492-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190492-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2011-08-04 | — | — | US | disclosed |
| US-7910579-B2 | Benzoxazole derivatives | TOHOKU UNIVERSITY (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7910579-B2 | Benzoxazole derivatives | TOHOKU UNIVERSITY (JP) | 2011-03-22 | — | — | US | disclosed |
| US-7910579-B2 | Benzoxazole derivatives | TOHOKU UNIVERSITY (JP) | 2011-03-22 | — | — | US | disclosed |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | TOHOKU UNIVERSITY (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | TOHOKU UNIVERSITY (JP) | 2010-01-28 | — | — | US | disclosed |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | TOHOKU UNIVERSITY (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2103611-A1 | BENZOXAZOLE DERIVATIVES | Tohoku University (JP) | 2009-09-23 | — | — | EP | disclosed |
| US-20090185975-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090185975-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2009-07-23 | — | — | US | disclosed |
| US-20090185975-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TOHOKU UNIVERSITY (JP) | 2009-07-23 | — | — | US | disclosed |
| EP-1967517-A1 | PROBE FOR DIAGNOSIS OF CONFORMATIONAL DISEASE | TOHOKU UNIVERSITY (JP) | 2008-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090185975-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TARDBP, LMNA, PMP22 | KDM4E 3776/4885ALDH1A1 2945/4885RAB9A 3592/4885 |
| US-20100021385-A1 | BENZOXAZOLE DERIVATIVES | CBX7, KIT, BMX | KDM4E 1190/4885ALDH1A1 1195/4885RAB9A 3587/4885 |
| US-20210220408-A1 | ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND METHODS OF USE | AHR, ARNT, ARSA | KDM4E 1784/4885ALDH1A1 98/4885RAB9A 4056/4885 |
| US-20110190492-A1 | DIAGNOSTIC PROBE FOR CONFORMATION DISEASE | TARDBP, LMNA, PMP22 | KDM4E 3776/4885ALDH1A1 2945/4885RAB9A 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.