Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 12/20 | 0.36 |
| ▸ | ACHE | P22303 | 12/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1983658 | 0.85 | TSHR (0.32) | TSHRLMNAMEN1MAPTKMT2A | |
| SCHEMBL29138441 | 0.85 | ESR1 (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7792042 | 0.82 | LMNA (0.41) | TSHRLMNAMEN1ALDH1A1KMT2A | |
| SCHEMBL3157247 | 0.80 | GABRA1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL15648819 | 0.79 | BDKRB2 (0.36) | TSHRLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL15648671 | 0.79 | BDKRB2 (0.36) | TSHRLMNAMEN1ALDH1A1MAPT | |
| SCHEMBL2871347 | 0.78 | HDAC8 (0.36) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL1452840 | 0.77 | HTT (0.38) | TSHRLMNAACHEMEN1ALDH1A1 | |
| SCHEMBL7862872 | 0.76 | LTA4H (0.31) | HDAC3HDAC1HDAC2 | |
| SCHEMBL5157292 | 0.75 | EBP (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864173-B | Process for converting substituted sodium arylsulfinates into aryltri-n-butyltin | 天津师范大学 | 2020-07-21 | — | — | CN | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| US-7910783-B2 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2011-03-22 | — | — | US | disclosed |
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2010-05-06 | — | — | US | disclosed |
| US-7709670-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-1866322-B1 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2010-02-24 | — | — | EP | disclosed |
| EP-1971621-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | ExxonMobil Chemical Patents Inc. (US) | 2008-09-24 | — | — | EP | disclosed |
| EP-1866322-A2 | PROCESS FOR PRODUCING SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | ExxonMobil Chemical Patents Inc. (US) | 2007-12-19 | — | — | EP | disclosed |
| WO-2007070045-A1 | PREPARATION OF SUBSTITUTED BRIDGED INDENYL AND RELATED LIGANDS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| WO-2003051896-A1 | CYTIDINE LIBRARIES AND COMPOUNDS SYNTHESIZED BY SOLID-PHASE COMBINATORIAL STRATEGIES | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051897-A1 | NUCLEOSIDE ANALOG LIBRARIES AND COMPOUNDS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051898-A1 | UNUSUAL NUCLEOSIDE LIBRARIES, COMPOUNDS, AND PREFERRED USES AS ANTIVIRAL AND ANTICANCER AGENTS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051899-A1 | DEAZAPURINE NUCLEOSIDE LIBRARIES AND COMPOUNDS | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |
| EP-0664282-B1 | Biaryl phospholipase A2 inhibitors | BRISTOL MYERS SQUIBB CO (US) | 1997-10-22 | — | — | EP | disclosed |
| EP-0664282-A1 | Biaryl phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-26 | — | — | EP | disclosed |
| US-5391817-A | Antiinflammatory agents | BRISTOL-MYERS SQUIBB (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0259972-B1 | HETEROCYCLIC PROPENE AMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICALS | LILLY INDUSTRIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| US-4983619-A | Leukotriene antagonists | LILLY INDUSTRIES LIMITED (GB) | 1991-01-08 | — | — | US | disclosed |
| EP-0259972-A2 | Heterocyclic propene amide derivatives, processes for their preparation and their use as pharmaceuticals | LILLY INDUSTRIES LIMITED (GB) | 1988-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | HDAC3 1399/4885HDAC1 1434/4885HDAC2 2348/4885 |
| US-20100113717-A1 | Process For Producing Substituted Metallocene Compounds For Olefin Polymerization | OSBP, OSBPL3, OSBP2 | HDAC3 3602/4885HDAC1 3517/4885HDAC2 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.