SCHEMBL145452

SCHEMBL145452

CC(F)(F)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA13 Q8N1Q1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776698 0.82 CA1 (0.33) CA1CA2CA7CA13
SCHEMBL14669110 0.82 CA1 (0.33) CA1CA2CA7CA13
Iodide SCHEMBL7252284 0.80 CA1 (0.32) CA1CA2CA7CA13
SCHEMBL5984726 0.78 CA1 (0.30) CA1CA2CA7CA13
SCHEMBL19520098 0.76
SCHEMBL286824 0.75 CA1 (0.37) CA1CA2CA7CA13
SCHEMBL10685320 0.74 ALDH1A1 (0.37)
SCHEMBL8649495 0.74 ALDH1A1 (0.37)
SCHEMBL25871898 0.74
SCHEMBL4124586 0.74 CA2 (0.32) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115411363-A Electrolyte, secondary battery and electric equipment 欣旺达电动汽车电池有限公司 2022-11-29 CN claimed
EP-2097401-A1 PROCESSES FOR THE PREPARATION OF (3R, 4R) -N- (4 -CHLOROPHENYL) -1- (2, 2-DIFLUOROETHYL) -N' - [2-FLUORO-4- (2-OXO-1 (2H) -PYRIDINYL) PHENYL]-3, 4-PYRROLIDINEDICARBOXAMIDE F. Hoffmann-Roche AG (CH) 2009-09-09 EP claimed
US-20080214826-A1 PROCESSES FOR THE MANUFACTURE OF A PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVE HOFFMANN-LA ROCHE, INC. 2008-09-04 US claimed
WO-2008077797-A1 PROCESSES FOR THE PREPARATION OF (3R, 4R) -N- (4 -CHLOROPHENYL) -1- (2, 2-DIFLUOROETHYL) -N' - [2-FLUORO-4- (2-OXO-1 (2H) -PYRIDINYL) PHENYL] -3, 4-PYRROLIDINEDICARBOXAMIDE F. HOFFMANN-LA ROCHE AG (CH) 2008-07-03 WO claimed
EP-4431509-B1 NOVEL NON-FLUORINATED QUINOLONE COMPOUND AND APPLICATION THEREOF GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO LTD BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) 2026-01-21 EP disclosed
US-12336991-B2 Factor XIIA inhibitors UNIVERSITY OF LEEDS (GB) 2025-06-24 US disclosed
US-20250042912-A1 NOVEL NON-FLUORINATED QUINOLONE COMPOUND AND USE THEREOF GUANGZHOU BAIYUNSHAN PHARMACEUTICAL HOLDINGS CO., LTD. BAIYUNSHAN PHARMACEUTICAL GENERAL FACTORY (CN) 2025-02-06 US disclosed
EP-4489738-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Kumquat Biosciences Inc. (US) 2025-01-15 EP disclosed
CN-118510758-A RXFP1 agonists 百时美施贵宝公司 2024-08-16 CN disclosed
CN-118355004-A Cyclopropyl- (heteroaryl) -substituted ethylsulfonyl-pyridine derivatives 勃林格殷格翰动物保健有限公司 2024-07-16 CN disclosed
CN-118339162-A Novel non-fluoroquinolone compounds and application thereof 广州白云山医药集团股份有限公司白云山制药总厂 2024-07-12 CN disclosed
CN-118317774-A Pharmaceutical compositions comprising quinazoline compounds 安斯泰来制药株式会社 2024-07-09 CN disclosed
WO-2008119663-A1 HETEROCYCLIC ANTIVIRAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 2008-10-09 WO disclosed
US-20080214826-A1 PROCESSES FOR THE MANUFACTURE OF A PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVE HOFFMANN-LA ROCHE, INC. 2008-09-04 US disclosed
WO-2008077797-A1 PROCESSES FOR THE PREPARATION OF (3R, 4R) -N- (4 -CHLOROPHENYL) -1- (2, 2-DIFLUOROETHYL) -N' - [2-FLUORO-4- (2-OXO-1 (2H) -PYRIDINYL) PHENYL] -3, 4-PYRROLIDINEDICARBOXAMIDE F. HOFFMANN-LA ROCHE AG (CH) 2008-07-03 WO disclosed
WO-2008071918-A1 PYRIDO-PYRAZINE DERIVATIVES USEFUL AS HERBICIDAL COMPOUNDS SYNGENTA LIMITED (GB) 2008-06-19 WO disclosed
EP-1047656-A4 ALKENYLDIARYLMETHANE NON-NUCLEOSIDE HIV-1 REVERSE TRANSCRIPTASE INHIBITORS PURDUE RESEARCH FOUNDATION (US) 2003-07-30 EP disclosed
US-6569897-B1 Such as 3',3\"-dibromo-4',4\"-dimethyoxy-5',5\"-bis(methyoxy carbonyl)-1,1-diphenylethene PURDUE RESEARCH FOUNDATION 2003-05-27 US disclosed
EP-1047656-A1 ALKENYLDIARYLMETHANE NON-NUCLEOSIDE HIV-1 REVERSE TRANSCRIPTASE INHIBITORS PURDUE RESEARCH FOUNDATION (US) 2000-11-02 EP disclosed
WO-1999036384-A1 ALKENYLDIARYLMETHANE NON-NUCLEOSIDE HIV-1 REVERSE TRANSCRIPTASE INHIBITORS PURDUE RESEARCH FOUNDATION (US) 1999-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042912-A1 NOVEL NON-FLUORINATED QUINOLONE COMPOUND AND USE THEREOF NQO2, Q6ZSR9, NRAS CA1 4133/4885CA2 3825/4885CA7 1717/4885
US-20080214826-A1 PROCESSES FOR THE MANUFACTURE OF A PYRROLIDINE-3,4-DICARBOXAMIDE DERIVATIVE ALDH18A1, CPS1, DHPS CA1 1825/4885CA2 1265/4885CA7 823/4885
US-12336991-B2 Factor XIIA inhibitors F11, F13B, F12 CA1 615/4885CA2 522/4885CA7 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.