Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | ALKBH2 | Q6NS38 | 4/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 4/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.39 |
| ▸ | PYGM | P11217 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171083 | 0.87 | CTSA (0.48) | CTSACSF1RFLT3GRM5FDPS | |
| SCHEMBL29580736 | 0.87 | CTSA (0.48) | CTSACSF1RFLT3GRM5FDPS | |
| SCHEMBL14480939 | 0.81 | KDM4C (0.57) | GRM5NPC1RAB9APYGLPYGM | |
| SCHEMBL107759 | 0.79 | CTSA (0.50) | CTSACSF1RFLT3GRM5FDPS | |
| SCHEMBL30275603 | 0.77 | TYK2 (0.45) | FDPSNPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL10274536 | 0.76 | KMT2A (0.50) | CTSACSF1RFLT3NPC1RAB9A | |
| SCHEMBL8486170 | 0.76 | CTSA (0.54) | CTSACSF1RFLT3GRM5FDPS | |
| SCHEMBL346168 | 0.76 | ANO1 (0.58) | CSF1RFLT3 | |
| SCHEMBL14574955 | 0.75 | ALDH1A1 (0.55) | NPC1RAB9APKMSMN1; SMN2 | |
| SCHEMBL13852609 | 0.75 | KMT2A (0.52) | CTSAGRM5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669369-B2 | Method and process for preparation and production of deuterated Ω-diphenylurea | SUZHOU ZELGEN BIOPHARMACEUTICAL CO., LTD. (CN) | 2014-03-11 | — | — | US | disclosed |
| US-20130060043-A1 | PREPARATION METHOD OF FLUORO-SUBSTITUTED DEUTERATED DIPHENYLUREA | SUZHOU ZELGEN BIOPHARMACEUTICAL CO., LTD (CN) | 2013-03-07 | — | — | US | disclosed |
| US-20130035492-A1 | METHOD AND PROCESS FOR PREPARATION AND PRODUCTION OF DEUTERATED OMEGA-DIPHENYLUREA | SUZHOU ZELGEN BIOPHARMACEUTICAL CO., LTD. | 2013-02-07 | — | — | US | disclosed |
| US-20130018209-A1 | PREPARATION METHODS OF METHYL-D3-AMINE AND SALTS THEREOF | SUZHOU ZELGEN BIOPHARMACEUTICAL CO., LTD. (CN) | 2013-01-17 | — | — | US | disclosed |
| US-20130012548-A1 | DEUTERIUM-SUBSTITUTED OMEGA-DIPHENYLUREA AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | SUZHOU ZELGEN BIOPHARMACEUTICAL CO., LTD. (CN) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130060043-A1 | PREPARATION METHOD OF FLUORO-SUBSTITUTED DEUTERATED DIPHENYLUREA | CCND3, UBE2D3, VDR | CTSA 2538/4885CSF1R 4714/4885FLT3 2441/4885 |
| US-20130012548-A1 | DEUTERIUM-SUBSTITUTED OMEGA-DIPHENYLUREA AND DERIVATIVES THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE COMPOUNDS | PPARD, HDHD5, SCD | CTSA 1348/4885CSF1R 4495/4885FLT3 559/4885 |
| US-20130035492-A1 | METHOD AND PROCESS FOR PREPARATION AND PRODUCTION OF DEUTERATED OMEGA-DIPHENYLUREA | PNLIP, PDXK, PNP | CTSA 3017/4885CSF1R 4755/4885FLT3 2261/4885 |
| US-20130018209-A1 | PREPARATION METHODS OF METHYL-D3-AMINE AND SALTS THEREOF | NSD3, CCND3, DRD3 | CTSA 4882/4885CSF1R 3403/4885FLT3 3002/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.