Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14560448 | 0.83 | EGFR (0.50) | ATMTDP1L3MBTL1EGFRKDM4E | |
| SCHEMBL14560443 | 0.75 | EGFR (0.64) | ATMTDP1L3MBTL1EGFRKDM4E | |
| SCHEMBL14560446 | 0.74 | RAD52 (0.49) | ATMTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL14560453 | 0.73 | ALDH1A1 (0.48) | ATMTDP1L3MBTL1EGFRKDM4E | |
| SCHEMBL14560449 | 0.72 | EGFR (0.47) | ATMTDP1L3MBTL1EGFRKDM4E | |
| SCHEMBL28826073 | 0.70 | L3MBTL1 (0.46) | ATMTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL14560451 | 0.70 | HTR6 (0.47) | ATMTDP1L3MBTL1EGFRKDM4E | |
| SCHEMBL26631768 | 0.70 | TDP1 (0.54) | ATMTDP1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL26631823 | 0.69 | L3MBTL1 (0.50) | ATMTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL1092376 | 0.68 | L3MBTL1 (0.55) | ATMTDP1L3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189721-B2 | Bicyclic protein kinase inhibitors | SUGEN INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189721-B2 | Bicyclic protein kinase inhibitors | SUGEN INC. (US) | 2007-03-13 | — | — | US | disclosed |