SCHEMBL14564280

SCHEMBL14564280

CCO[Si]1(OCC)C[Si](OCC)(OCC)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.33
HTR1A P08908 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
MAPK1 P28482 2/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 4/20 0.32
ALDH1A1 P00352 4/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14573756 0.76 TP53 (0.32) TP53TSHR
SCHEMBL23000917 0.68 TP53 (0.33) TP53TSHRALDH1A1KMT2ASMN1; SMN2
SCHEMBL2863484 0.67 LTA4H (0.33) TP53TSHRMEN1NPC1KMT2A
SCHEMBL24769797 0.60 SLC1A3 (0.43) TP53MAPK1MAPTL3MBTL1TSHR
SCHEMBL16478 0.59 TSHR (0.70) TP53MAPK1MAPTTDP1L3MBTL1
SCHEMBL13434101 0.58 HTR1A (0.74) HTR1AADRA1DADRA1AADRA1BMAPK1
Ammonia Solution, Strong SCHEMBL2308512 0.57 TSHR (0.67) TP53MAPK1MAPTTDP1L3MBTL1
SCHEMBL25430960 0.57 TSHR (0.67) TP53MAPK1MAPTTDP1L3MBTL1
Bromide SCHEMBL20577438 0.57 TSHR (0.67) TP53MAPK1MAPTTDP1L3MBTL1
SCHEMBL2435561 0.57 TSHR (0.52) TP53HTR1AADRA1DADRA1AADRA1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070054136-A1 Film forming composition, insulating film and production process of the insulating film FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
US-20070036991-A1 Film-forming composition, insulating film and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070054136-A1 Film forming composition, insulating film and production process of the insulating film SGMS1, SPTLC1, SGMS2 TP53 2258/4885HTR1A 2190/4885ADRA1D 4074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.