Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ASPH | Q12797 | 1/20 | 0.46 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.46 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CD38 | P28907 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11754772 | 0.84 | KDM4E (0.49) | FFAR1HDAC1KDM4EASPHRIOX2 | |
| SCHEMBL11890771 | 0.80 | HDAC1 (0.53) | HDAC1KDM4EASPHRIOX2KDM8 | |
| SCHEMBL12004538 | 0.80 | GAA (0.54) | HDAC1KDM4EASPHRIOX2KDM8 | |
| SCHEMBL1445627 | 0.78 | F2RL1 (0.73) | FFAR1F2RL1MAPTALDH1A1LMNA | |
| SCHEMBL12061580 | 0.78 | HDAC1 (0.51) | FFAR1HDAC1KDM4EASPHRIOX2 | |
| SCHEMBL18046156 | 0.76 | ALDH1A1 (0.53) | F2RL1HDAC1KDM4EMAPTALDH1A1 | |
| SCHEMBL9683167 | 0.76 | HTT (0.51) | MAPTNCF1GAALMNANPC1 | |
| SCHEMBL9683331 | 0.76 | MAP2K4 (0.52) | HDAC1MAPTNCF1GAALMNA | |
| SCHEMBL9725455 | 0.76 | VNN1 (0.57) | HDAC1KDM4EASPHRIOX2KDM8 | |
| SCHEMBL3949236 | 0.76 | GAA (0.57) | ALDH1A1GAALMNAL3MBTL1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070066606-A1 | Benzylbenzimidazolyl derivatives | MERCK PATENT GMBH (DE) | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066606-A1 | Benzylbenzimidazolyl derivatives | TIE1, KDR, FLT1 | FFAR1 792/4885F2RL1 205/4885HDAC1 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.