Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 8/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22561848 | 0.89 | RORC (0.38) | RORCNOTUMPDE3BPDE3A | |
| SCHEMBL23666664 | 0.85 | AKR1C3 (0.34) | S1PR1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL21125077 | 0.82 | UBE2M (0.38) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL10624896 | 0.81 | NOTUM (0.44) | RORCNOTUMPDE3BPDE3AS1PR1 | |
| SCHEMBL21124971 | 0.81 | AKR1C3 (0.41) | S1PR1AKR1C3AKR1C2 | |
| SCHEMBL27378583 | 0.81 | ALOX15 (0.42) | RORCAKR1C3AKR1C2TP53CYP2D6 | |
| SCHEMBL21124509 | 0.77 | PDE2A (0.39) | S1PR1AKR1C3AKR1C2PDE2AAKR1B10 | |
| SCHEMBL24767423 | 0.77 | AR (0.52) | — | |
| SCHEMBL16952207 | 0.76 | NOTUM (0.41) | RORCNOTUMPDE3BPDE3AS1PR1 | |
| SCHEMBL21725488 | 0.75 | IDO1 (0.39) | RORCPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054909-A1 | VLA-4 inhibitor compounds | VCAM1, ITGB4, ICAM1 | RORC 307/4885NOTUM 3050/4885PDE3B 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.