Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA5A | P35218 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL1458005 | 0.94 | HSD11B1 (0.32) | MEN1USP2TP53POLBMAPT | |
| SCHEMBL4388126 | 0.90 | MEN1 (0.37) | MEN1USP2TP53POLBMAPT | |
| SCHEMBL1087889 | 0.82 | GPR3 (0.34) | PTPN1GPR3CA1CA2CA5A | |
| SCHEMBL7569683 | 0.79 | CA1 (0.35) | PTPN1GPR3CA1CA2 | |
| SCHEMBL8528959 | 0.79 | HSD11B1 (0.31) | HSD11B1PTPN1GPR3CA1CA2 | |
| SCHEMBL546606 | 0.78 | GPR3 (0.36) | HSD11B1PTPN1GPR3CA1CA2 | |
| SCHEMBL217001 | 0.78 | GPR3 (0.36) | HSD11B1PTPN1GPR3CA1CA2 | |
| SCHEMBL5872604 | 0.78 | GPR3 (0.36) | PTPN1GPR3CA1CA2CA5A | |
| SCHEMBL1482705 | 0.77 | CA2 (0.38) | PTPN1GPR3CA1CA2 | |
| SCHEMBL51399 | 0.77 | CA2 (0.38) | PTPN1GPR3CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300507-B1 | ANTIRELECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA (US) | 2014-02-26 | — | — | EP | disclosed |
| US-8329387-B2 | Antireflective coating compositions | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2012-12-11 | — | — | US | disclosed |
| EP-2300507-A1 | ANTIRELECTIVE COATING COMPOSITIONS | AZ Electronic Materials USA Corp. (US) | 2011-03-30 | — | — | EP | disclosed |
| WO-2010004378-A1 | ANTIRELECTIVE COATING COMPOSITIONS | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20100009297-A1 | Antireflective Coating Compositions | MERCK PATENT GMBH (DE) | 2010-01-14 | — | — | US | disclosed |