Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AKR1A1 | P14550 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31195728 | 0.71 | ITGA4 (1.00) | ITGA4AKR1B1ALDH1A1AKR1A1TDP1 | |
| SCHEMBL9810959 | 0.71 | ITGA4 (1.00) | ITGA4AKR1B1ALDH1A1AKR1A1TDP1 | |
| SCHEMBL3973309 | 0.70 | CYP2C9 (0.52) | AKR1B1ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL22709486 | 0.69 | SMN1; SMN2 (0.96) | ITGA4SMN1; SMN2GSK3BS100A4ALDH1A1 | |
| SCHEMBL16626076 | 0.66 | PDK2 (0.44) | ITGA4SMN1; SMN2GSK3BS100A4ALDH1A1 | |
| SCHEMBL10602199 | 0.65 | GSK3B (0.48) | ITGA4SMN1; SMN2GSK3BAKR1B1S100A4 | |
| SCHEMBL357510 | 0.65 | MEN1 (0.55) | ITGA4SMN1; SMN2GSK3BS100A4ALDH1A1 | |
| SCHEMBL31598409 | 0.65 | S100A4 (0.58) | ITGA4SMN1; SMN2GSK3BS100A4ALDH1A1 | |
| SCHEMBL30833582 | 0.65 | MEN1 (0.55) | ITGA4SMN1; SMN2GSK3BS100A4ALDH1A1 | |
| SCHEMBL30501016 | 0.65 | MEN1 (0.55) | ITGA4SMN1; SMN2GSK3BS100A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | KEYNEUROTEK PHARMACEUTICALS AG (DE) | 2007-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037785-A1 | Novel dipeptidyl peptidase IV inhibitors used for functionally influencing different cells and treating immunological, infammatory, neuronal, and other diseases | DNPEP, PREP, DPP4 | ITGA4 3348/4885SMN1; SMN2 4098/4885GSK3B 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.