Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.65 |
| ▸ | PPARA | Q07869 | 3/20 | 0.60 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | CTSK | P43235 | 10/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922945 | 0.86 | KLK7 (0.51) | CTSSPPARAPPARGCTSKCTSB | |
| SCHEMBL3905825 | 0.82 | CTSS (0.47) | CTSSCTSKCTSBCTSL | |
| SCHEMBL7928203 | 0.82 | CTSS (0.49) | CTSSCTSKCTSBCTSL | |
| SCHEMBL13596697 | 0.81 | PPARA (0.74) | CTSSPPARAPPARGCTSKCTSB | |
| SCHEMBL14234760 | 0.80 | CTSS (0.46) | CTSSCTSKCTSBCTSL | |
| SCHEMBL828674 | 0.79 | PPARA (0.90) | CTSSPPARAPPARGCTSKCTSB | |
| SCHEMBL1132901 | 0.79 | PPARA (0.90) | CTSSPPARAPPARGCTSKCTSB | |
| SCHEMBL17051 | 0.79 | PPARA (0.90) | CTSSPPARAPPARGCTSKCTSB | |
| SCHEMBL29229102 | 0.78 | PPARA (0.76) | CTSSPPARAPPARGCTSKCTSB | |
| SCHEMBL7057256 | 0.78 | PPARA (0.76) | CTSSPPARAPPARGCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070027067-A1 | Transition-state Inhibitors of Pin1, alpha-Ketoamide-containing peptidomimetics, and synthesis thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027067-A1 | Transition-state Inhibitors of Pin1, alpha-Ketoamide-containing peptidomimetics, and synthesis thereof | PIN1, PREP, PIN4 | CTSS 2669/4885PPARA 2892/4885PPARG 3478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.