Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 11/20 | 0.49 |
| ▸ | CTSL | P07711 | 9/20 | 0.49 |
| ▸ | CTSB | P07858 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 8/20 | 0.47 |
| ▸ | KYNU | Q16719 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922945 | 0.92 | KLK7 (0.51) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL18103764 | 0.90 | KYNU (0.51) | CTSSCTSLCTSBCTSKKYNU | |
| SCHEMBL18103765 | 0.90 | KYNU (0.51) | CTSSCTSLCTSBCTSKKYNU | |
| SCHEMBL18103837 | 0.87 | CASP1 (0.53) | CTSSCTSLCTSBCTSKKYNU | |
| SCHEMBL7928236 | 0.86 | KYNU (0.46) | CTSSCTSLCTSBCTSKKYNU | |
| SCHEMBL14583259 | 0.82 | CTSS (0.65) | CTSSCTSLCTSBCTSK | |
| SCHEMBL6812701 | 0.81 | CTSS (0.52) | CTSSCTSLCTSBCTSKKYNU | |
| Water SCHEMBL2580712 | 0.81 | PPARA (0.56) | CTSSCTSLCTSBCTSKSYK | |
| Water SCHEMBL29401166 | 0.81 | PPARA (0.56) | CTSSCTSLCTSBCTSKSYK | |
| SCHEMBL478289 | 0.80 | PPARA (0.57) | CTSSCTSLCTSBCTSKSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235929-B1 | SELECTIVELY INHIBITING SERINE PROTEASES, SELECTIVELY INHIBITING CYSTEINE PROTEASES, | GEORGIA TECH RESEARCH CORPORATION | 2001-05-22 | — | — | US | disclosed |
| US-5763576-A | Tetrapeptide α-ketoamides | GEORGIA TECH RESEARCH CORP. (US) | 1998-06-09 | — | — | US | disclosed |