Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587772 | 0.84 | ALDH1A1 (0.43) | PPARGNTRK1ALDH1A1 | |
| SCHEMBL14587693 | 0.83 | RAB9A (0.46) | PPARGNTRK1ALDH1A1PTGESHTT | |
| SCHEMBL14587735 | 0.83 | NTRK1 (0.54) | PPARGNTRK1ALDH1A1HTTRECQL | |
| SCHEMBL14587723 | 0.80 | PPARG (0.47) | PPARGHTT | |
| SCHEMBL14587722 | 0.80 | NTRK1 (0.54) | PPARGNTRK1ALDH1A1 | |
| SCHEMBL14587847 | 0.79 | PPARG (0.44) | PPARGNTRK1ALDH1A1HTTRECQL | |
| SCHEMBL5012182 | 0.79 | PPARG (0.56) | PPARGHDAC1HDAC6 | |
| SCHEMBL13933572 | 0.79 | POLB (0.34) | PPARGNTRK1HTTRECQL | |
| SCHEMBL5010840 | 0.79 | NR1H4 (0.53) | PPARGHDAC6NR1H4 | |
| SCHEMBL14587849 | 0.78 | PPARG (0.43) | PPARGNTRK1ALDH1A1PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | JAPAN TOBACCO INC. (JP) | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032529-A1 | Pyrazole compounds and their use as antidiabetes agents | PYGL, GYS2, AGL | PPARG 706/4885NTRK1 4549/4885ALDH1A1 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.