Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | AKT2 | P31751 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790799 | 0.81 | ALOX15 (0.36) | ALOX15AKT2GSK3BHRH3JAK3 | |
| SCHEMBL6281359 | 0.75 | AKT2 (0.49) | ALOX15AKT2GSK3BHRH3HIPK2 | |
| SCHEMBL24419090 | 0.75 | GRIN2B (0.57) | GRIN2BGRIN2A | |
| SCHEMBL300491 | 0.72 | ALOX15 (0.41) | ALOX15AKT2JAK3HIPK2F2RL1 | |
| SCHEMBL6840293 | 0.71 | NPC1 (0.41) | HRH3HRH4 | |
| Hydrochloric Acid SCHEMBL9200760 | 0.70 | ALOX15 (0.39) | ALOX15JAK3HIPK2F2RL1HTR2B | |
| SCHEMBL311710 | 0.70 | BCHE (0.42) | ALOX15AKT2HRH3JAK3HIPK2 | |
| Hydrochloric Acid SCHEMBL29956711 | 0.70 | HIPK2 (0.37) | ALOX15AKT2GSK3BJAK3HIPK2 | |
| SCHEMBL14587776 | 0.70 | TRPC3 (0.68) | — | |
| SCHEMBL556899 | 0.69 | LMNA (0.39) | HIPK2F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | ALOX15 778/4885AKT2 3360/4885GSK3B 4572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.