Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | RORA | P35398 | 1/20 | 0.51 |
| ▸ | RORC | P51449 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601744 | 0.81 | GAA (0.62) | ALDH1A1HTTHDAC1MEN1GAA | |
| SCHEMBL23852173 | 0.80 | RAD51 (0.72) | ALDH1A1HTTHDAC1RAD51MEN1 | |
| SCHEMBL6981195 | 0.75 | ALDH1A1 (0.60) | ALDH1A1HTTPFKFB3TSHRHDAC1 | |
| SCHEMBL14601737 | 0.75 | RAD51 (0.66) | ALDH1A1HTTHDAC1PGRRAD51 | |
| SCHEMBL14601742 | 0.75 | PKM (0.58) | ALDH1A1HDAC1PGRPTPN2PTPN1 | |
| SCHEMBL3259317 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTPFKFB3TSHRHDAC1 | |
| SCHEMBL9616665 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HTTPFKFB3TSHRHDAC1 | |
| SCHEMBL3261087 | 0.75 | TSHR (0.71) | ALDH1A1HTTPFKFB3TSHRHDAC1 | |
| SCHEMBL9480187 | 0.74 | ALDH1A1 (0.62) | ALDH1A1HTTPFKFB3TSHRHDAC1 | |
| SCHEMBL812673 | 0.74 | TSHR (0.74) | ALDH1A1HTTPFKFB3TSHRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
| US-20070021509-A1 | Phosphate transport inhibitors | JOZEFIAK THOMAS H | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021509-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC20A1 | ALDH1A1 2163/4885HTT 2299/4885PFKFB3 459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.