Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21228838 | 0.86 | ALDH1A1 (0.58) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL29191713 | 0.85 | ALDH1A1 (0.50) | ALDH1A1GAAMGAMSIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL22780 | 0.84 | GAA (0.67) | ALDH1A1GAAMGAMSIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL27768067 | 0.84 | GAA (0.67) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL6081987 | 0.83 | GAA (0.54) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL8788095 | 0.82 | ALDH1A1 (0.41) | ALDH1A1GAAMGAMSIMGAM2 | |
| SCHEMBL8788323 | 0.82 | ALDH1A1 (0.41) | ALDH1A1GAAMGAMSIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL4324913 | 0.82 | GAA (0.63) | ALDH1A1GAAMGAMSIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL21815758 | 0.82 | GAA (0.63) | ALDH1A1GAAMGAMSIMGAM2 | |
| Succinic Acid Diethyl Ester SCHEMBL29494609 | 0.82 | GAA (0.63) | ALDH1A1GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033307-A1 | NILOTINIB DIHYDROCHLORIDE SALT | GENERICS [UK] LIMITED (GB) | 2011-03-24 | — | — | WO | claimed |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | FUDAN UNIVERSITY (CN) | 2023-12-05 | — | — | US | disclosed |
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-06-22 | — | — | US | disclosed |
| US-9260438-B2 | Solid forms of tofacitinib salts | APOTEX INC. (CA) | 2016-02-16 | — | — | US | disclosed |
| US-20160024251-A1 | THERMORESPONSIVE POLYESTERS | THE UNIVERSITY OF AKRON | 2016-01-28 | — | — | US | disclosed |
| US-20150225406-A1 | SOLID FORMS OF TOFACITINIB SALTS | APOTEX INC. (CA) | 2015-08-13 | — | — | US | disclosed |
| WO-2011033307-A1 | NILOTINIB DIHYDROCHLORIDE SALT | GENERICS [UK] LIMITED (GB) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | SULT2A1, NIT2, CA2 | ALDH1A1 139/4885GAA 3119/4885MGAM 3466/4885 |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | SULT2A1, NIT2, CA2 | ALDH1A1 131/4885GAA 3013/4885MGAM 3266/4885 |
| US-20150225406-A1 | SOLID FORMS OF TOFACITINIB SALTS | JAK3, JAK2, JAK1 | ALDH1A1 4512/4885GAA 3284/4885MGAM 2088/4885 |
| US-20160024251-A1 | THERMORESPONSIVE POLYESTERS | COASY, CD14, NCAPH | ALDH1A1 1850/4885GAA 4062/4885MGAM 2186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.