SCHEMBL2760850

SCHEMBL2760850

CNCC(O)c1ccc(O)c(O)c1Cl

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 6/20 0.66
ADRA2B P18089 6/20 0.66
ADRA2C P18825 6/20 0.66
ADRA1A P35348 3/20 0.66
ADRB1 P08588 5/20 0.49
ADRB3 P13945 4/20 0.49
ADRB2 P07550 4/20 0.49
TDP1 Q9NUW8 4/20 0.49
KDM4E B2RXH2 4/20 0.49
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HIF1A Q16665 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CYP2D6 P10635 1/20 0.49
DRD2 P14416 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11850533 0.83 ADRB1 (0.68) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL11841871 0.82 ADRB2 (0.56) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL1461292 0.81 ADRA2A (0.68) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL9767993 0.81 ADRA2A (0.68) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL9768011 0.79 ADRA2A (1.00) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL29278698 0.79 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL29852847 0.79 ADRA2A (1.00) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL2250 0.78 ADRA2A (0.61) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL28535211 0.77 ADRA2A (0.62) ADRA2AADRA2BADRA2CADRA1AADRB1
SCHEMBL11849771 0.75 ADRB2 (0.52) ADRA2AADRA2BADRA2CADRA1AADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240108869-A1 Active Agent Delivery Devices and Methods of Using the same GLAS USA LLC 2024-04-04 US disclosed
US-20240082147-A1 Active Agent Loaded Uniform, Rigid, Spherical, Nanoporous Calcium Phosphate Particles and Methods of Making and Using the Same LABORATORY SKIN CARE, INC. 2024-03-14 US disclosed
US-11865286-B2 Active agent delivery devices and methods of using the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-01-09 US disclosed
US-20230414512-A1 Dermal Delivery Compositions Comprising Active Agent-Calcium Phosphate Particle Complexes and Methods of Using the Same LABORATORY SKIN CARE, INC. 2023-12-28 US disclosed
EP-4218718-A2 DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME Laboratory Skin Care, Inc. (US) 2023-08-02 EP disclosed
US-20230216595-A1 PHARMA-INFORMATICS SYSTEM OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2023-07-06 US disclosed
EP-2427178-B1 DERMAL DELIVERY COMPOSITIONS COMPRISING ACTIVE AGENT-CALCIUM PHOSPHATE PARTICLE COMPLEXES AND METHODS OF USING THE SAME LABORATORY SKIN CARE INC (US) 2023-01-04 EP disclosed
US-11476952-B2 Pharma-informatics system OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-10-18 US disclosed
US-20210220276-A1 Methods of Treating Skin LABORATORY SKIN CARE, INC. 2021-07-22 US disclosed
EP-3827747-A1 PHARMA-INFORMATICS SYSTEM Otsuka Pharmaceutical Co., Ltd. (JP) 2021-06-02 EP disclosed
US-20020143579-A1 System and method for targeted interventions of physician prescription practices based on deviations from expert guidelines COMPREHENSIVE CLINICAL DEVELOPMENT, INC. (FKA COMPREHENSIVE NEUROSCIENCE, INC.) 2002-10-03 US disclosed
EP-0861084-B1 IMPROVED PROCESS AND COMPOSITION FOR THERAPEUTIC CISPLATIN (CDDP) MATRIX PHARMA (US) 2002-06-19 EP disclosed
US-6224883-B1 SUPPLYING TO TUMOR, CANCER MATRIX PHARMACEUTICAL, INC. 2001-05-01 US disclosed
US-6077545-A PHOTOSENSITIVE COMPOSITION, ACID GENERATOR AND ORGANOSILICON COMPOUND MATRIX PHARMACEUTICALS, INC. (US) 2000-06-20 US disclosed
EP-0861084-A4 IMPROVED PROCESS AND COMPOSITION FOR THERAPEUTIC CISPLATIN (CDDP) MATRIX PHARMA (US) 2000-02-02 EP disclosed
US-5925682-A ANTITUMOR AGENTS IMMUNOTECH INC. (US) 1999-07-20 US disclosed
EP-0861084-A1 IMPROVED PROCESS AND COMPOSITION FOR THERAPEUTIC CISPLATIN (CDDP) Matrix Pharmaceutical, Inc. (US) 1998-09-02 EP disclosed
EP-0833608-A2 REVERSE FLUOROCARBON EMULSION COMPOSITIONS FOR DRUG DELIVERY ALLIANCE PHARMACEUTICAL CORPORATION (US) 1998-04-08 EP disclosed
WO-1997016196-A1 IMPROVED PROCESS AND COMPOSITION FOR THERAPEUTIC CISPLATIN (CDDP) MATRIX PHARMACEUTICAL INC. (US) 1997-05-09 WO disclosed
WO-1996040057-A2 REVERSE FLUOROCARBON EMULSION COMPOSITIONS FOR DRUG DELIVERY ALLIANCE PHARMACEUTICAL CORP. (US) 1996-12-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240082147-A1 Active Agent Loaded Uniform, Rigid, Spherical, Nanoporous Calcium Phosphate Particles and Methods of Making and Using the Same CHERP, ORAI1, CA2 ADRA2A 2908/4885ADRA2B 4410/4885ADRA2C 3846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.