Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.62 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.62 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7333737 | 0.95 | PLA2G2A (0.69) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL9664224 | 0.95 | PLA2G2A (0.69) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL18088347 | 0.94 | PLA2G2A (0.56) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL11676490 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL542910 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL23833964 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL7325048 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL25183155 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL8006368 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 | |
| SCHEMBL4741208 | 0.93 | PLA2G2A (0.72) | PLA2G2APLA2G5NOD1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NICOX SA (FR) | 2014-09-25 | — | — | US | disclosed |
| EP-2731453-A1 | FLAVOUR MODIFYING COMPOUNDS | Givaudan SA (CH) | 2014-05-21 | — | — | EP | disclosed |
| US-20140127144-A1 | Flavour Modifying Compounds | GIVAUDAN S. A. (CH) | 2014-05-08 | — | — | US | disclosed |
| WO-2013010991-A1 | FLAVOUR MODIFYING COMPOUNDS | GIVAUDAN SA (CH) | 2013-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140127144-A1 | Flavour Modifying Compounds | TAS2R1, TAS1R2, TAS2R5 | PLA2G2A 3369/4885PLA2G5 2123/4885NOD1 1315/4885 |
| US-20140288142-A1 | NITRIC OXIDE DONOR COMPOUNDS | NOS3, NOS2, NOS1 | PLA2G2A 1738/4885PLA2G5 1012/4885NOD1 1456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.