SCHEMBL1463952

SCHEMBL1463952

CC(C)(C)N(CC(=O)O)CP(=O)(O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.36
LMNA P02545 2/20 0.36
TSHR P16473 2/20 0.36
BLM P54132 2/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36
KMT2A Q03164 1/20 0.36
MVD P53602 2/20 0.32
EYA2 O00167 1/20 0.31
APP P05067 1/20 0.31
ACE P12821 1/20 0.31
GRM4 Q14833 1/20 0.30
ADRA1A P35348 2/20 0.30
HMGCR P04035 1/20 0.30
CHRM1 P11229 1/20 0.30
TBXA2R P21731 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRA2A P08913 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482378 0.84 MEN1 (0.33) TDP1LMNATSHRBLMMEN1
SCHEMBL10716447 0.84 TSHR (0.33) TDP1LMNATSHRBLMMEN1
SCHEMBL783010 0.79 TDP1 (0.41) TDP1LMNATSHRBLMEYA2
SCHEMBL6673078 0.74 LMNA (0.35) TDP1LMNATSHRBLMMEN1
SCHEMBL3871128 0.73 FFAR3 (0.36) TDP1LMNATSHRBLMEYA2
SCHEMBL10482393 0.72
SCHEMBL14199728 0.71 TDP1 (0.35) TDP1LMNATSHRBLMEYA2
SCHEMBL22291050 0.71 TDP1 (0.35) TDP1LMNATSHRBLMEYA2
SCHEMBL10197374 0.71 TDP1 (0.35) TDP1LMNATSHRBLMEYA2
SCHEMBL126893 0.71 MVD (0.46) TDP1LMNATSHRBLMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450523-B2 Process for preparation of a carboxylic acid salt by dehydrogenation of a primary alcohol MONSANTO TECHNOLOGY LLC (US) 2013-05-28 US disclosed
US-8298985-B2 Catalyst for dehydrogenating primary alcohols MONSANTO TECHNOLOGY LLC (US) 2012-10-30 US disclosed
EP-1272451-B1 PROCESS AND CATALYST FOR DEHYDROGENATING PRIMARY ALCOHOLS TO MAKE CARBOXYLIC ACID SALTS MONSANTO TECHNOLOGY LLC (US) 2012-08-01 EP disclosed
US-20120190889-A1 PROCESS FOR PREPARATION OF A CARBOXYLIC ACID SALT BY DEHYDROGENATION OF A PRIMARY ALCOHOL MONSANTO TECHNOLOGY LLC (US) 2012-07-26 US disclosed
US-20110071027-A1 HIGH STRENGTH AQUEOUS GLYPHOSATE SALT CONCENTRATES AND METHODS HELM AGRO US, INC. 2011-03-24 US disclosed
US-20110071018-A1 CATALYST FOR DEHYDROGENATING PRIMARY ALCOHOLS MONSANTO TECHNOLOGY LLC (US) 2011-03-24 US disclosed
US-20110071026-A1 LOW VISCOSITY, AQUEOUS GLYPHOSATE SALT CONCENTRATES HELM AGRO US, INC. 2011-03-24 US disclosed
US-7329778-B2 Process and catalyst for dehydrogenating primary alcohols to make carboxylic acid salts MONSANTO TECHNOLOGY LLC (US) 2008-02-12 US disclosed
US-7297657-B2 Process for the preparation of N-(phosphonomethyl)glycine by oxidizing N-substituted N-(phosphonomethyl)glycine MONSANTO TECHNOLOGY LLC (US) 2007-11-20 US disclosed
EP-1716923-A1 Oxidation catalyst for making glyphosate Monsanto Technology, LLC (US) 2006-11-02 EP disclosed
US-4657705-A Process for the preparation of N-substituted aminomethylphosphonic acids MONSANTO COMPANY (US) 1987-04-14 US disclosed
EP-0216744-A2 The compound 1,4-diisopropyl-2,5-diketopiperazine Monsanto Company (US) 1987-04-01 EP disclosed
EP-0216745-A1 Process for the preparation of N-substituted aminomethylphosphonic acids Monsanto Company (US) 1987-04-01 EP disclosed
US-4654429-A Process for the preparation of a glyphosate product MONSANTO COMPANY (US) 1987-03-31 US disclosed
US-4617415-A α-Substituted N-phosphonomethyliminodiacetic acid MONSANTO COMPANY (US) 1986-10-14 US disclosed
EP-0187633-A1 Thermal dealkylation of n-alkyl n-phosphonomethylglycine Monsanto Company (US) 1986-07-16 EP disclosed
EP-0186647-A1 Process for preparing glyphosate and glyphosate derivatives Monsanto Company (US) 1986-07-02 EP disclosed
EP-0186648-A1 Process for the preparation of glyphosate and glyphosate derivatives Monsanto Company (US) 1986-07-02 EP disclosed
US-4568432-A REACTING OXO-AMINES WITH CARBONYLPHOSPHONIC COMPOUND, THEN REDUCTION MONSANTO COMPANY (US) 1986-02-04 US disclosed
US-3927080-A Process for producing N-phosphonomethyl glycine MONSANTO CO 1975-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071026-A1 LOW VISCOSITY, AQUEOUS GLYPHOSATE SALT CONCENTRATES SLC6A5, SLC7A1, SLC6A9 TDP1 711/4885LMNA 3030/4885TSHR 3269/4885
US-20110071027-A1 HIGH STRENGTH AQUEOUS GLYPHOSATE SALT CONCENTRATES AND METHODS SLC6A5, SLC6A9, SLC7A1 TDP1 1830/4885LMNA 3077/4885TSHR 3328/4885
US-20120190889-A1 PROCESS FOR PREPARATION OF A CARBOXYLIC ACID SALT BY DEHYDROGENATION OF A PRIMARY ALCOHOL ADH1A, ADH1C, ADH5 TDP1 4616/4885LMNA 3425/4885TSHR 2495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.