Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | TIMP3 | P35625 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.52 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.47 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14640094 | 0.93 | NT5E (0.61) | NT5EKMT2ATIMP3MEN1RECQL | |
| SCHEMBL14601341 | 0.91 | TIMP3 (0.64) | KMT2ATIMP3MEN1RECQLHSD17B10 | |
| SCHEMBL11761517 | 0.91 | TIMP3 (0.64) | KMT2ATIMP3MEN1RECQLHSD17B10 | |
| SCHEMBL14107312 | 0.91 | TIMP3 (0.64) | KMT2ATIMP3MEN1RECQLHSD17B10 | |
| SCHEMBL11761453 | 0.90 | TIMP3 (0.63) | KMT2ATIMP3MEN1RECQLHSD17B10 | |
| SCHEMBL11757461 | 0.87 | CASP6 (0.60) | NT5EKMT2ATIMP3MEN1RECQL | |
| SCHEMBL12215086 | 0.87 | ENPP2 (0.55) | NT5EKMT2ATIMP3MEN1RECQL | |
| SCHEMBL17115738 | 0.86 | ENPP2 (0.61) | KMT2ATIMP3MEN1RECQLHSD17B10 | |
| SCHEMBL11760372 | 0.84 | TIMP3 (0.64) | NT5EKMT2ATIMP3MEN1RECQL | |
| SCHEMBL14601340 | 0.84 | TIMP3 (0.64) | NT5EKMT2ATIMP3MEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | MEDICAL RESEARCH COUNCIL (GB) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070003987-A1 | Screening method for substance binding to merozoite surface protein-1/42 | CD2BP2, MASP2, CD14 | NT5E 2596/4885KMT2A 4666/4885TIMP3 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.