Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.41 |
| ▸ | USP2 | O75604 | 5/20 | 0.41 |
| ▸ | RECQL | P46063 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901964 | 0.88 | ALOX15 (0.41) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL11136076 | 0.82 | ALOX15 (0.59) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL10062117 | 0.82 | ALOX15 (0.59) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL849961 | 0.82 | ALOX15 (0.59) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL13612126 | 0.81 | TAAR1 (0.50) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL11981918 | 0.79 | ALDH1A1 (0.45) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL12532003 | 0.78 | SLC7A5 (0.69) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL10135632 | 0.78 | SLC7A5 (0.69) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL523988 | 0.78 | THRB (0.44) | KDM4EHSD17B10ALOX15USP2RECQL | |
| SCHEMBL17771942 | 0.78 | CA2 (0.49) | KDM4EHSD17B10ALOX15USP2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008603-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2007-01-18 | — | — | WO | disclosed |