SCHEMBL18901964

SCHEMBL18901964

NC(C=O)Cc1ccc(N=O)c(O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.41
KDM4E B2RXH2 4/20 0.41
SLC7A5 Q01650 4/20 0.41
RECQL P46063 3/20 0.41
HIF1A Q16665 3/20 0.41
HSD17B10 Q99714 3/20 0.41
USP2 O75604 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
HTR2A P28223 2/20 0.41
PTGS2 P35354 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
EGFR P00533 2/20 0.41
LCK P06239 1/20 0.41
FYN P06241 1/20 0.41
PTGS1 P23219 1/20 0.41
PLA2G1B P04054 1/20 0.36
ALOX12 P18054 4/20 0.35
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
ALDH1A1 P00352 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14640359 0.88 KDM4E (0.41) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL10062117 0.82 ALOX15 (0.59) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL11136076 0.82 ALOX15 (0.59) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL849961 0.82 ALOX15 (0.59) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL11981918 0.76 ALDH1A1 (0.45) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL17771942 0.74 CA2 (0.49) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL523988 0.74 THRB (0.44) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL17479954 0.74 THRB (0.44) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL26381603 0.74 ALOX15 (0.47) ALOX15KDM4ESLC7A5RECQLHIF1A
SCHEMBL20275281 0.73 ALOX15 (0.71) ALOX15KDM4ESLC7A5RECQLHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3173098-A1 IMMUNOSTIMULATORY COMPOSITIONS ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (FR) 2017-05-31 EP disclosed