SCHEMBL14647243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647115	0.89	PARP1 (0.43)	HTR7DRD4KHKPOLBPARP1
	SCHEMBL14647217	0.89	DRD4 (0.48)	HTR7DRD4DRD2DRD3HTR1A
	SCHEMBL14647195	0.83	HTR7 (0.47)	HTR7DRD4DRD2DRD3KDM4E
	SCHEMBL14647187	0.83	DRD4 (0.43)	HTR7DRD4DRD2DRD3HTR1A
	SCHEMBL14647224	0.83	DRD4 (0.52)	HTR7DRD4DRD2DRD3KDM4E
	SCHEMBL14647183	0.83	PARP1 (0.46)	DRD4DRD2DRD3POLBMAPT
	SCHEMBL14647158	0.83	MAPT (0.48)	HTR7DRD4KDM4EMAPTPARP1
	SCHEMBL14647276	0.83	DRD4 (0.54)	HTR7DRD4DRD2DRD3KDM4E
	SCHEMBL14647242	0.82	PARP1 (0.51)	HTR7DRD4DRD2DRD3KDM4E
	SCHEMBL14647223	0.82	SIGMAR1 (0.45)	HTR7KDM4EPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.