SCHEMBL14647229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647234	0.90	LMNA (0.46)	SMN1; SMN2LMNATSHRHTTMAPT
	SCHEMBL14647240	0.84	PARP1 (0.44)	SMN1; SMN2MAPK1KDM4EMAPTGAA
	SCHEMBL14647180	0.83	SMN1; SMN2 (0.51)	SMN1; SMN2LMNAMAPK1KDM4ETSHR
	SCHEMBL14647202	0.82	MAPT (0.56)	SMN1; SMN2LMNAMAPK1KDM4ETSHR
	SCHEMBL14647127	0.79	POLB (0.46)	SMN1; SMN2LMNAKDM4ETSHRMAPT
	SCHEMBL14647178	0.79	MAPT (0.52)	SMN1; SMN2LMNAMAPK1KDM4ETSHR
	SCHEMBL14647114	0.75	CSNK2A1 (0.43)	KDM4EMAPTALDH1A1MEN1KMT2A
	SCHEMBL14647161	0.73	MGLL (0.52)	SMN1; SMN2LMNAMAPK1KDM4ETSHR
	SCHEMBL14647261	0.72	MGLL (0.49)	SMN1; SMN2LMNAMAPK1KDM4ETSHR
	SCHEMBL14647149	0.72	MAPT (0.55)	SMN1; SMN2LMNAMAPK1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.