Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.49 |
| ▸ | RAF1 | P04049 | 5/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668761 | 0.83 | PPARG (0.52) | ARRAF1CDK8PPARGPPARA | |
| SCHEMBL29623436 | 0.83 | AR (0.47) | ARCDK8TLR8CYP1A2CYP3A4 | |
| SCHEMBL27533351 | 0.81 | RAB9A (0.53) | ARRAF1CDK8PPARGPPARA | |
| SCHEMBL14649870 | 0.80 | KMO (0.56) | GAAMAPT | |
| SCHEMBL14649764 | 0.77 | AR (0.41) | ARRAF1PPARGPPARAIDO1 | |
| SCHEMBL12733300 | 0.76 | AR (0.40) | ARRAF1CDK8PPARGPPARA | |
| SCHEMBL876310 | 0.76 | AR (0.45) | ARRAF1PPARGPPARAGPR84 | |
| SCHEMBL876272 | 0.76 | AR (0.49) | ARRAF1CDK8PPARGPPARA | |
| SCHEMBL6511184 | 0.76 | MAOA (0.50) | ARRAF1CDK8CYP3A4GAA | |
| SCHEMBL18235652 | 0.76 | AR (0.49) | ARRAF1CDK8PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013010758-A1 | NEMATOCIDE N- CYCLOPROPYL - SULFONYLAMIDE DERIVATIVES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-24 | — | — | WO | disclosed |