SCHEMBL146547

SCHEMBL146547

C=C(C)C(=O)Oc1ccccc1SCC

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30747871 1.00 PTGS2 (0.56) PTGS2
SCHEMBL6863145 0.83 ELANE (0.47) PTGS2
SCHEMBL24244892 0.81 PKM (0.40) PTGS2
SCHEMBL7079229 0.80 ELANE (0.45) PTGS2
SCHEMBL27594051 0.80 ELANE (0.45) PTGS2
SCHEMBL30747872 0.79 PTGS2 (0.55) PTGS2
SCHEMBL146227 0.79 PTGS2 (0.55) PTGS2
SCHEMBL30803748 0.78 ELANE (0.56) PTGS2
SCHEMBL30803750 0.78 ELANE (0.56) PTGS2
SCHEMBL1232932 0.78 ELANE (0.56) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023218463-A1 RADIATION INDUCED RADICAL CURING BY SEMICONDUCTING NANOPARTICLES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2023-11-16 WO claimed
EP-2303331-B1 OPHTHALMIC DEVICE HAVING THERAPEUTIC AGENT DELIVERY CAPABILITY AND METHOD OF FORMING SAME ALCON INC (CH) 2022-01-26 EP claimed
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2018-12-06 US claimed
EP-2292672-B1 Biocompatible polymers and co-polymers comprising amino acids in the side chain CIS PHARMA AG (CH) 2018-05-09 EP claimed
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof HITZ HANS (CH) 2017-06-01 US claimed
EP-1888660-B1 BIOCOMPATIBLE POLYMERS AND CO-POLYMERS COMPRISING AMINO ACIDS IN THE SIDE CHAIN CIS PHARMA AG (CH) 2017-05-17 EP claimed
US-8980957-B2 Methods for the preparation of biocompatible polymers, the polymers and their uses CIS PHARMA AG (CH) 2015-03-17 US claimed
US-8901218-B2 Branched (meth)acrylate copolymer with high refractive index and method for preparing the same CHEIL INDUSTRIES INC. (KR) 2014-12-02 US claimed
EP-2341104-B1 Polycarbonate resin composition with excellent scratch resistance and impact strength CHEIL IND INC (KR) 2014-11-12 EP claimed
US-20140242722-A1 ARTICLE AND METHOD FOR DETECTION OF A DRUG IN A LIQUID MEDIUM MEDTECH DETECT, LLC (US) 2014-08-28 US claimed
WO-2005026787-A1 PROCESS FOR MANUFACTURING INTRAOCULAR LENSES WITH BLUE LIGHT ABSORPTION CHARACTERISTICS BAUSCH & LOMB INCORPORATED (US) 2005-03-24 WO claimed
US-20050055090-A1 Process for manufacturing intraocular lenses with blue light absorption characteristics BAUSCH HEALTH US, LLC 2005-03-10 US claimed
EP-0914169-B1 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LAB INC (US) 2003-07-30 EP claimed
EP-0914169-A3 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 2002-08-28 EP claimed
US-6353069-B1 INTRAOCULAR LENSES THAT HAVE HIGH REFRACTIVE INDEXES, ARE FLEXIBLE AND TRANSPARENT, CAN BE INSERTED INTO EYE THROUGH RELATIVELY SMALL INCISION, RECOVER ORIGINAL SHAPE AFTER HAVING BEEN INSERTED, AND ARE FREE OF GLISTENINGS ALCON MANUFACTURING, LTD. 2002-03-05 US claimed
EP-1080382-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS Alcon Laboratories, Inc. (US) 2001-03-07 EP claimed
US-6001128-A CROSSLINKED ACRYLATED ESTER ALCON LABORATORIES, INC. (US) 1999-12-14 US claimed
WO-1999053347-A1 HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS ALCON LABORATORIES, INC. (US) 1999-10-21 WO claimed
EP-0914169-A2 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 1999-05-12 EP claimed
WO-1998053862-A2 MATERIALS FOR USE IN GLAUCOMA FILTRATION DEVICES ALCON LABORATORIES, INC. (US) 1998-12-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170152335-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 PTGS2 880/4885
US-20180346629-A1 Biocompatible polymers and co-polymers, and uses thereof ARG1, CRYAA, COL1A1 PTGS2 880/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.