Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.51 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | FLT4 | P35916 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.46 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209446 | 0.83 | LMNA (0.65) | MEP1BPGRKEAP1NFE2L2FFAR4 | |
| SCHEMBL6968304 | 0.82 | MMP2 (0.57) | ALDH1A1GAA | |
| SCHEMBL14676410 | 0.81 | KMT2A (0.53) | ALDH1A1LMNA | |
| SCHEMBL10402270 | 0.80 | BCAT1 (0.50) | L3MBTL1KEAP1ALDH1A1LMNAKAT6A | |
| SCHEMBL14675852 | 0.79 | MAPT (0.47) | PGRLMNAKAT6AKDRGAA | |
| SCHEMBL14675686 | 0.79 | PGR (0.53) | PGRLMNAKDRFLT1FLT4 | |
| SCHEMBL14677369 | 0.79 | ATM (0.54) | PGRALDH1A1LMNAKAT6AKDR | |
| SCHEMBL24926381 | 0.78 | PARG (0.55) | MEP1BPGRL3MBTL1KEAP1NFE2L2 | |
| SCHEMBL14676933 | 0.77 | GAA (0.53) | L3MBTL1ALDH1A1GAA | |
| SCHEMBL14677195 | 0.77 | CA1 (0.61) | PGRALDH1A1KAT6AGAAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073830-B2 | Compound for inhibiting 11β-hydroxy steroid dehydrogenase 1, and a pharmaceutical composition comprising the same | HYUNDAI PHARM CO., LTD. (KR) | 2015-07-07 | — | — | US | disclosed |
| US-20140206875-A1 | A COMPOUND FOR INHIBITING 11B-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2014-07-24 | — | — | US | disclosed |
| WO-2013019091-A2 | A COMPOUND FOR INHIBITING 11β-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HYUNDAI PHARM CO., LTD. (KR) | 2013-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206875-A1 | A COMPOUND FOR INHIBITING 11B-HYDROXY STEROID DEHYDROGENASE 1, AND A PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | HSD11B1, HSD11B2, HSD17B1 | MEP1B 725/4885PGR 961/4885L3MBTL1 4633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.