Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12305402 | 0.97 | BACE1 (0.64) | BACE1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL4198689 | 0.92 | LMNA (0.55) | BACE1KDM4EACHEALDH1A1GLA | |
| SCHEMBL14700515 | 0.92 | BACE1 (0.51) | BACE1SMN1; SMN2KDM4EACHEALDH1A1 | |
| SCHEMBL17860073 | 0.86 | BACE1 (0.46) | BACE1KDM4EACHEALDH1A1GLA | |
| SCHEMBL28663436 | 0.85 | SLC2A1 (0.54) | BACE1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL28656189 | 0.84 | HSD17B10 (0.66) | BACE1KDM4EACHEALDH1A1LMNA | |
| SCHEMBL5582943 | 0.84 | ACHE (0.58) | SMN1; SMN2KDM4EACHEALDH1A1GLA | |
| SCHEMBL4085836 | 0.84 | HSD17B1 (0.64) | BACE1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL16488962 | 0.83 | BACE1 (0.55) | BACE1SMN1; SMN2KDM4ECYP1A2CYP2D6 | |
| SCHEMBL679848 | 0.82 | SMN1; SMN2 (0.55) | BACE1SMN1; SMN2KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040234-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE | FUJI ELECTRIC CO., LTD. (JP) | 2013-02-14 | — | — | US | disclosed |