SCHEMBL28656189

SCHEMBL28656189

CC(=O)Oc1ccc(-c2ccc(C(=O)O)cc2)c(C)c1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.66
GAA P10253 2/20 0.52
LMNA P02545 1/20 0.52
HSD17B1 P14061 1/20 0.49
ADH5 P11766 1/20 0.47
KDM4E B2RXH2 2/20 0.46
ELANE P08246 1/20 0.46
EPHX1 P07099 1/20 0.46
RARB P10826 2/20 0.46
BACE1 P56817 3/20 0.46
ACHE P22303 1/20 0.45
HCRTR1 O43613 1/20 0.45
HCRTR2 O43614 1/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
RAB9A P51151 1/20 0.45
SRD5A2 P31213 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28671630 0.91 HSD17B10 (0.66) HSD17B10GAALMNAHSD17B1ADH5
SCHEMBL4198689 0.89 LMNA (0.55) HSD17B10GAALMNAHSD17B1KDM4E
SCHEMBL28663436 0.85 SLC2A1 (0.54) HSD17B10GAALMNAHSD17B1KDM4E
SCHEMBL14700488 0.84 BACE1 (0.59) HSD17B10LMNAHSD17B1KDM4EEPHX1
SCHEMBL12305402 0.84 BACE1 (0.64) HSD17B10LMNAHSD17B1KDM4EEPHX1
SCHEMBL17860073 0.83 BACE1 (0.46) HSD17B10GAALMNAHSD17B1KDM4E
SCHEMBL28654333 0.83 CA12 (0.46) HSD17B10LMNAHSD17B1KDM4EALDH1A1
SCHEMBL5582943 0.82 ACHE (0.58) GAALMNAKDM4EELANEACHE
SCHEMBL3750003 0.81 RXRA (0.61) ADH5RARBHCRTR1HCRTR2SRD5A2
SCHEMBL31628308 0.80 ADH5 (0.56) GAAHSD17B1ADH5KDM4ERARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN claimed
CN-113748021-B Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2024-07-05 CN disclosed
CN-113748021-A Method for producing liquid crystal polyester processed product 本州化学工业株式会社 2021-12-03 CN disclosed