Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822520 | 0.86 | ESR1 (0.52) | BACE1TSHRESR1ESR2CHRM5 | |
| SCHEMBL14287530 | 0.78 | ESR1 (0.49) | BACE1MEN1KMT2AESR1ESR2 | |
| SCHEMBL14700552 | 0.78 | ALOX5 (0.41) | MEN1KMT2ATSHRESR1ESR2 | |
| SCHEMBL14700590 | 0.78 | CHRM5 (0.40) | TSHRESR1ESR2CHRM5 | |
| SCHEMBL14700587 | 0.78 | CFD (0.53) | CFDFFAR1BACE1MEN1KMT2A | |
| SCHEMBL17148016 | 0.77 | BACE1 (0.44) | BACE1MAOBMEN1KMT2AADORA3 | |
| SCHEMBL29609097 | 0.77 | SLC6A9 (0.44) | RARARARBRARGSLC6A9ESR1 | |
| SCHEMBL22187702 | 0.77 | SLC6A9 (0.44) | RARARARBRARGSLC6A9ESR1 | |
| SCHEMBL10016827 | 0.76 | CFD (0.54) | CFDFFAR1BACE1MEN1KMT2A | |
| SCHEMBL12578507 | 0.76 | ESR1 (0.49) | MEN1KMT2AESR1ESR2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040234-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE | FUJI ELECTRIC CO., LTD. (JP) | 2013-02-14 | — | — | US | disclosed |