SCHEMBL14700552

SCHEMBL14700552

COc1ccc(C2(c3ccc(OC(C)=O)c(C)c3)c3ccccc3Oc3ccccc32)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
CHRM5 P08912 4/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
MAPT P10636 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HTT P42858 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
EDNRB P24530 2/20 0.36
EDNRA P25101 2/20 0.36
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NR3C1 P04150 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822520 0.86 ESR1 (0.52) CHRM5TSHRESR1ESR2MAPT
SCHEMBL14700590 0.83 CHRM5 (0.40) CHRM5POLBTSHRESR1ESR2
SCHEMBL14287530 0.79 ESR1 (0.49) CHRM5ESR1ESR2MAPTMEN1
SCHEMBL14700520 0.78 CFD (0.39) CHRM5TSHRESR1ESR2MEN1
SCHEMBL14701780 0.77 LMNA (0.36) ESR1ESR2MAPTMEN1KMT2A
SCHEMBL22651232 0.76 ESR1 (0.70) CHRM5POLBESR1ESR2MAPT
SCHEMBL15395858 0.74 ALDH1A1 (0.42) CHRM5POLBTSHRMAPTALDH1A1
SCHEMBL13446409 0.74 ESR1 (0.49) CHRM5TSHRESR1ESR2MAPT
SCHEMBL12578507 0.74 ESR1 (0.49) CHRM5ESR1ESR2MAPTMEN1
SCHEMBL21075509 0.74 ESR1 (0.49) CHRM5POLBESR1ESR2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed