SCHEMBL14701193

SCHEMBL14701193

CC(COC(=O)/C(C#N)=C/c1ccc(N2CCOCC2)cc1)OC(=O)/C(C#N)=C/c1ccc(N2CCOCC2)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.59
MAPT P10636 8/20 0.59
KMT2A Q03164 6/20 0.59
MEN1 O00255 5/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MAPK1 P28482 1/20 0.59
CASP3 P42574 1/20 0.59
SENP8 Q96LD8 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
APP P05067 3/20 0.56
HPGD P15428 1/20 0.52
POLB P06746 2/20 0.49
LMNA P02545 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12435542 0.85 ALDH1A1 (0.80) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL14701210 0.78 IDE (0.61) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL15373528 0.77 MAPT (0.91) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL15491114 0.77 ALDH1A1 (0.58) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL14701163 0.76 ALDH1A1 (0.59) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL14701183 0.75 IDE (0.58) ALDH1A1MAPTKMT2AMEN1RAB9A
SCHEMBL14701194 0.75 ALDH1A1 (0.80) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL14703185 0.75 MAPT (0.56) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL17120618 0.75 MEN1 (0.65) ALDH1A1MAPTKMT2AMEN1NPC1
SCHEMBL14701178 0.74 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AMEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
US-8664289-B2 Dye and coloring photosensitive composition ADEKA CORPORATION (JP) 2014-03-04 US disclosed
EP-2620476-A1 PIGMENT AND COLORED PHOTOSENSITIVE COMPOSITION Adeka Corporation (JP) 2013-07-31 EP disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION ADEKA CORPORATION (JP) 2013-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130041062-A1 DYE AND COLORING PHOTOSENSITIVE COMPOSITION IK, CRY1, ABCG2 ALDH1A1 155/4885MAPT 458/4885KMT2A 3478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.