SCHEMBL14701717

SCHEMBL14701717

CCC(C)(CC)Oc1ccc(Cc2ccc(OC(=O)C(C)(C)CC)c(C)c2)cc1C

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
ELANE P08246 1/20 0.36
CFD P00746 1/20 0.36
VDR P11473 1/20 0.36
OPRK1 P41145 1/20 0.36
PPARG P37231 2/20 0.35
FBP1 P09467 1/20 0.34
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34
PPARA Q07869 3/20 0.33
PPARD Q03181 2/20 0.33
ALOX15 P16050 1/20 0.33
FFAR4 Q5NUL3 2/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
HIF1A Q16665 1/20 0.32
FFAR1 O14842 1/20 0.32
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12907945 0.86 VDR (0.42) VDRFBP1ESR1ALDH1A1AR
SCHEMBL14701777 0.85 VDR (0.41) VDRFBP1ESR1ALDH1A1AR
SCHEMBL13063796 0.85 ALOX15 (0.47) L3MBTL1CFDVDROPRK1PPARG
SCHEMBL22013498 0.84 ALDH1A1 (0.36) L3MBTL1ELANEVDRPPARGFBP1
SCHEMBL14342686 0.80 ESR1 (0.59) ESR1ESR2AR
SCHEMBL14679469 0.80 L3MBTL1 (0.37) L3MBTL1ELANECFDVDROPRK1
SCHEMBL15395809 0.76 VDR (0.41) ELANEVDRESR1ESR2ALDH1A1
SCHEMBL22238643 0.76 VDR (0.37) VDRPPARGFBP1PPARAPPARD
SCHEMBL14754930 0.75 VDR (0.42) VDRFBP1ESR1ALDH1A1AR
SCHEMBL12040652 0.75 VDR (0.42) VDRFBP1ESR1ALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed