Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.68 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17699233 | 0.87 | NOTUM (0.56) | P2RX7CA1CA2NOTUMCA9 | |
| SCHEMBL25160211 | 0.81 | P2RX7 (0.68) | P2RX7CA1CA2PTGS2CA5A | |
| SCHEMBL14610999 | 0.81 | P2RX7 (0.68) | P2RX7FLT3CA1CA2PTGS2 | |
| SCHEMBL24569989 | 0.81 | P2RX7 (0.68) | P2RX7FLT3CA1CA2PTGS2 | |
| SCHEMBL2819653 | 0.81 | P2RX7 (1.00) | P2RX7CA1CA2PTGS2CA5A | |
| SCHEMBL4960613 | 0.77 | P2RX7 (0.62) | P2RX7CA1CA2PTGS2CA5A | |
| SCHEMBL4963203 | 0.77 | P2RX7 (0.67) | P2RX7CA1CA2PTGS2CA5A | |
| SCHEMBL12156465 | 0.76 | P2RX7 (0.60) | P2RX7PTGS2AMY1A | |
| SCHEMBL31568332 | 0.76 | P2RX7 (0.47) | P2RX7CA1CA2NOTUMCA9 | |
| SCHEMBL16827649 | 0.76 | P2RX7 (0.47) | P2RX7FLT3POLBRXRAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884848-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2018-02-06 | — | — | US | disclosed |
| US-9884848-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2018-02-06 | — | — | US | disclosed |
| US-9884848-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2018-02-06 | — | — | US | disclosed |
| EP-2885290-B1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA AS (DK) | 2017-10-18 | — | — | EP | disclosed |
| EP-2885290-B1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA AS (DK) | 2017-10-18 | — | — | EP | disclosed |
| US-20170114045-A1 | PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA AS (DK) | 2017-04-27 | — | — | US | disclosed |
| US-20170114045-A1 | PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA AS (DK) | 2017-04-27 | — | — | US | disclosed |
| US-20170114045-A1 | PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA AS (DK) | 2017-04-27 | — | — | US | disclosed |
| US-9475797-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2016-10-25 | — | — | US | disclosed |
| US-9475797-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2016-10-25 | — | — | US | disclosed |
| US-9475797-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2016-10-25 | — | — | US | disclosed |
| US-20160115155-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA APS (DK) | 2016-04-28 | — | — | US | disclosed |
| US-20160115155-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA APS (DK) | 2016-04-28 | — | — | US | disclosed |
| US-20160115155-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA APS (DK) | 2016-04-28 | — | — | US | disclosed |
| US-9284350-B2 | IAP BIR domain binding compounds | PHARMASCIENCE INC. (CA) | 2016-03-15 | — | — | US | disclosed |
| EP-2885290-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABA RECEPTOR COMPLEX | SANIONA APS (DK) | 2015-06-24 | — | — | EP | disclosed |
| CN-104411703-A | A phenyl triazole derivative and its use for modulating the gabaa receptor complex | ANIONA APS | 2015-03-11 | — | — | CN | disclosed |
| WO-2014001282-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | ANIONA APS (DK) | 2014-01-03 | — | — | WO | disclosed |
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | PHARMASCIENCE INC. (CA) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040892-A1 | IAP BIR DOMAIN BINDING COMPOUNDS | BIRC5, BIRC2, BIRC3 | P2RX7 4451/4885FLT3 4483/4885CA1 3367/4885 |
| US-20170114045-A1 | PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | GABRA5, GABRB3, GABRB1 | P2RX7 163/4885FLT3 1578/4885CA1 3598/4885 |
| US-20160115155-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | GABRB3, GABRB1, GABRB2 | P2RX7 191/4885FLT3 1646/4885CA1 3251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.