Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 14/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17704937 | 0.88 | NOTUM (0.70) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL14701726 | 0.87 | P2RX7 (0.68) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL30723667 | 0.74 | NOTUM (0.72) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL19127484 | 0.74 | MIF (0.55) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL17502287 | 0.72 | NOTUM (1.00) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL20639902 | 0.72 | NOTUM (0.70) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL19211396 | 0.72 | NOTUM (1.00) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL13728552 | 0.72 | NOTUM (0.70) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL31049690 | 0.72 | NOTUM (0.70) | NOTUMKDM4EMAPTL3MBTL1CA12 | |
| SCHEMBL28173683 | 0.72 | RXRA (0.54) | NOTUMKDM4EMAPTL3MBTL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884848-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2018-02-06 | — | — | US | disclosed |
| US-20170114045-A1 | PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA AS (DK) | 2017-04-27 | — | — | US | disclosed |
| US-9475797-B2 | Phenyl triazole derivative and its use for modulating the GABAA receptor complex | SANIONA A/S (DK) | 2016-10-25 | — | — | US | disclosed |
| US-20160115155-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | SANIONA APS (DK) | 2016-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114045-A1 | PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | GABRA5, GABRB3, GABRB1 | NOTUM 4074/4885KDM4E 1830/4885MAPT 1089/4885 |
| US-20160115155-A1 | A PHENYL TRIAZOLE DERIVATIVE AND ITS USE FOR MODULATING THE GABAA RECEPTOR COMPLEX | GABRB3, GABRB1, GABRB2 | NOTUM 4243/4885KDM4E 2237/4885MAPT 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.