Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21957469 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL21957470 | 0.81 | KDM4E (0.42) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL11738607 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL11738617 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7196153 | 0.77 | TSHR (0.40) | ALDH1A1KDM4EGAAMAPTHSD17B10 | |
| SCHEMBL8464142 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL8464139 | 0.74 | ALDH1A1 (0.39) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL23178917 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAMAPTSMN1; SMN2 | |
| SCHEMBL10564524 | 0.73 | NFE2L2 (0.55) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL10564520 | 0.73 | NFE2L2 (0.55) | ALDH1A1KDM4EMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130045952-A1 | ABA Receptor Agonists for Increased Plant Stress Resistance | VAN ANDEL RESEARCH INSTITUTE (US) | 2013-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130045952-A1 | ABA Receptor Agonists for Increased Plant Stress Resistance | BROX, AAK1, ADORA3 | ALDH1A1 3422/4885KDM4E 3079/4885GAA 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.