Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897753 | 0.80 | POLB (0.48) | HSD11B1GAATP53P2RX7POLB | |
| SCHEMBL14711534 | 0.80 | HPGD (0.47) | HSD11B1GAAPOLB | |
| SCHEMBL14794814 | 0.80 | OPRM1 (0.40) | HSD11B1GAATP53P2RX7POLB | |
| SCHEMBL14710585 | 0.74 | DGAT1 (0.41) | — | |
| SCHEMBL16569553 | 0.73 | CHRM5 (0.33) | CTSLCTSBCTSSSLC6A4SLC6A3 | |
| SCHEMBL16569143 | 0.73 | SLC6A2 (0.34) | CTSLCTSBCTSSSLC6A2SLC6A4 | |
| SCHEMBL14710344 | 0.73 | CTSL (0.39) | CTSLCTSBCTSSHSD11B1SLC6A2 | |
| SCHEMBL5365203 | 0.71 | P2RX7 (0.56) | P2RX7POLB | |
| SCHEMBL723702 | 0.71 | DRD2 (0.47) | SLC6A2SLC6A4SLC6A3P2RX7 | |
| SCHEMBL18112004 | 0.71 | HSD11B1 (0.49) | HSD11B1SLC6A4SLC6A3P2RX7POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013025733-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. (US) | 2013-02-21 | — | — | WO | disclosed |