Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27989644 | 0.91 | KMT2A (0.49) | KMT2APPARAFOLH1PTGER1PTGER4 | |
| SCHEMBL27947274 | 0.91 | DPP4 (0.44) | KMT2APPARAFOLH1PTGER1PTGER4 | |
| Phosphoric Acid SCHEMBL28716195 | 0.86 | ALDH1A1 (0.46) | ALDH1A1S1PR2S1PR4S1PR1S1PR3 | |
| SCHEMBL6527163 | 0.85 | DPP4 (0.47) | KMT2APPARAFOLH1PTGER1PTGER4 | |
| Phosphoric Acid SCHEMBL14331163 | 0.84 | PPARA (0.52) | PPARACYSLTR2CYSLTR1 | |
| Phosphoric Acid SCHEMBL28235490 | 0.84 | PPARA (0.52) | PPARACYSLTR2CYSLTR1 | |
| Phosphoric Acid SCHEMBL28398440 | 0.82 | ALDH1A1 (0.42) | ALDH1A1S1PR2S1PR4S1PR1S1PR3 | |
| Phosphoric Acid SCHEMBL3370739 | 0.81 | MGLL (0.49) | ALDH1A1PPARA | |
| Phosphoric Acid SCHEMBL11072237 | 0.81 | MGLL (0.49) | ALDH1A1PPARA | |
| Phosphoric Acid SCHEMBL28166823 | 0.80 | PPARA (0.48) | KMT2APPARAFOLH1PTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106895388-A | The intelligent light velocity steam machine equipment of energy-saving safe | 芜湖顺景自动化设备有限公司 | 2017-06-27 | — | — | CN | claimed |
| CN-106842366-A | A kind of weather warning equipment based on single-chip microcomputer long-distance intelligent control | 芜湖顺景自动化设备有限公司 | 2017-06-13 | — | — | CN | claimed |
| CN-112961311-A | Crystalline high modulus thermoplastic polyurethane | 路博润先进材料公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-108368226-B | Crystalline high modulus thermoplastic polyurethane | 路博润先进材料公司 | 2021-03-02 | — | — | CN | disclosed |
| CN-108473649-A | High modulus thermoplastic polyurethane | 路博润先进材料公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108368226-A | CRYSTALLINE HIGH MODULUS THERMOPLASTIC POLYURETHANE | 路博润先进材料公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-106895388-A | The intelligent light velocity steam machine equipment of energy-saving safe | 芜湖顺景自动化设备有限公司 | 2017-06-27 | — | — | CN | disclosed |
| EP-2562216-B1 | COMPATIBILIZED BLENDS OF BIODEGRADABLE POLYMERS WITH IMPROVED RHEOLOGY | NOVAMONT SPA (IT) | 2017-06-21 | — | — | EP | disclosed |
| CN-106842366-A | A kind of weather warning equipment based on single-chip microcomputer long-distance intelligent control | 芜湖顺景自动化设备有限公司 | 2017-06-13 | — | — | CN | disclosed |
| EP-2562216-A2 | Compatibilized blends of biodegradable polymers with improved rheology | Eastman Chemical Company (US) | 2013-02-27 | — | — | EP | disclosed |
| CN-101831116-B | Flame retardant rubber and application thereof in seismic isolation support seat | JIANGSU YANGZHOU HELI RUBBER PRODUCTS CO LTD | 2013-02-20 | — | — | CN | disclosed |
| CN-101831116-A | Flame retardant rubber and application thereof in seismic isolation support seat | JIANGSU YANGZHOU HELI RUBBER PRODUCTS CO LTD | 2010-09-15 | — | — | CN | disclosed |