Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493537 | 0.75 | TNKS (0.63) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL2461750 | 0.73 | XDH (0.48) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL215399 | 0.72 | XDH (0.50) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL5492728 | 0.72 | XDH (0.48) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL1473043 | 0.72 | ADRA2A (0.35) | XDHTNKSTNKS2GABRA1GABRB2 | |
| SCHEMBL1514254 | 0.72 | XDH (0.52) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL4465266 | 0.72 | XDH (0.52) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL8635421 | 0.71 | XDH (0.47) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL3806192 | 0.71 | XDH (0.47) | XDHTNKSTNKS2PARP1GABRA1 | |
| SCHEMBL719239 | 0.71 | XDH (0.47) | XDHTNKSTNKS2PARP1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11472763-B2 | Calixarene compound, curable composition, and cured product | DIC CORPORATION (JP) | 2022-10-18 | — | — | US | disclosed |
| US-20210198178-A1 | CALIXARENE COMPOUND, CURABLE COMPOSITION, AND CURED PRODUCT | DIC CORPORATION (JP) | 2021-07-01 | — | — | US | disclosed |
| US-7915438-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2011-03-29 | — | — | US | disclosed |
| US-7585928-B2 | monomers of acetylenic homo- or copolymers; cured polymers has low dielectric constant as insulating layers in microelectronic devices | DOW GLOBAL TECHNOLOGIES (US) | 2009-09-08 | — | — | US | disclosed |
| US-7271259-B1 | Solid phase host compositions | NORTHWESTERN UNIVERSITY (US) | 2007-09-18 | — | — | US | disclosed |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | DOW GLOBAL TECHNOLOGIES LLC | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210198178-A1 | CALIXARENE COMPOUND, CURABLE COMPOSITION, AND CURED PRODUCT | H1-0, CAPN1, CROCC | PTPRB 4443/4885XDH 1984/4885TNKS 3708/4885 |
| US-11472763-B2 | Calixarene compound, curable composition, and cured product | CAPN1, H1-0, CROCC | PTPRB 4419/4885XDH 2041/4885TNKS 3694/4885 |
| US-20070027278-A1 | Multifunctional monomers containing bound mesogenic poragen forming moieties and polyarylene compositions therefrom | LRBA, CD74, BMP2 | PTPRB 600/4885XDH 3820/4885TNKS 3146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.